StatementClassOfStock [Axis]
Series A Preferred Stock [Member]
Series B Preferred Stock [Member]
Series C Preferred Stock [Member]
StatementEquityComponents [Axis]
Common Stock [Member]
Additional Paid-in Capital [Member]
Treasury Stock [Member]
Accumulated Deficit [Member]
Long-term Debt, Type [Axis]
Notes Payable 1 [Member]
RelatedPartyTransactionsByRelatedParty [Axis]
CRL [Member]
NatureOfExpense [Axis]
Research and Development Expense [Member]
Options [Member]
General and Administrative Expense [Member]
Antidilutive Securities [Axis]
2016 (formerly 2008) and 1999 Stock Incentive Plans [Member]
Warrant [Member]
ClassOfWarrantOrRight [Axis]
Warrant 1 [Member]
Warrant 2 [Member]
Warrant 3 [Member]
Warrant 4 [Member]
Warrant 5 [Member]
Warrant 6 [Member]
Property, Plant and Equipment, Type [Axis]
Laboratory Equipment [Member]
Tenant Improvements [Member]
Computers and Network Equipment [Member]
Office Furniture And Equipment [Member]
Plan Name [Axis]
2016 Plan
Equity Components [Axis]
Series A Preferred Stock
Series B Preferred Stock
Series C Preferred Stock
Treasury Stock
Range [Axis]
Minimum [Member]
Maximum [Member]
Document And Entity Information
Entity Registrant Name
Entity Central Index Key
Document Type
Document Period End Date
Amendment Flag
Current Fiscal Year End Date
Is Entity's Reporting Status Current?
Entity Filer Category
Entity Emerging Growth Company
Entity Small Business
Entity Shell Company
Entity Common Stock, Shares Outstanding
Document Fiscal Period Focus
Document Fiscal Year Focus
Entity Interactive Data Current
Entity Incorporation State Country Code
Entity File Number
Trading Symbol
Title of 12b security
Security Exchange Name
Statement [Table]
Statement [Line Items]
Class of Stock [Axis]
ASSETS
Current assets:
Cash and cash equivalents
Receivable from supplier
Prepaid expenses and other current assets
Total current assets
Property and equipment, net
Right of use asset - operating lease
Security deposits and other assets
Total assets
LIABILITIES AND STOCKHOLDERS' EQUITY
Current liabilities:
Accounts payable
Accrued expenses
Current notes payable
Operating lease oligation
Financing lease obligation
Total current liabilities
Non-current liabilities:
Accrued dividends on Series B Preferred Stock
Deferred rent liability
Operating lease obligation
Financing lease obligations
Total non-current liabilities
Total liabilities
Commitments and contingencies
Stockholders' equity:
Preferred stock
Common stock, $0.001 par value; 100,000,000 shares authorized at June 30, 2019 and March 31, 2019; 42,758,630 shares issued and outstanding at June 30, 2019 and March 31, 2019
Additional paid-in capital
Treasury stock, at cost, 135,665 shares of common stock held at June 30, 2019 and March 31, 2019
Accumulated deficit
Total stockholders' equity
Total liabilities and stockholders' equity
Stockholders deficit:
Preferred Stock, par value
Preferred Stock, authorized
Preferred Stock, issued
Preferred Stock, outstanding
Common Stock, par value
Common Stock, authorized
Common Stock, issued
Common Stock, outstanding
Treasury Stock
Income Statement [Abstract]
Operating expenses:
Research and development
General and administrative
Total operating expenses
Loss from operations
Other income (expenses), net:
Interest income (expense), net
Loss on extinguishment of accounts payable
Loss before income taxes
Income taxes
Net loss and comprehensive loss
Accrued dividends on Series B Preferred stock
Deemed dividend from trigger of down round provision feature
Net loss attributable to common stockholders
Basic and diluted net loss attributable to common stockholders per common share
Weighted average shares used in computing basic and diluted net loss attributable to common stockholders per common share
Statement of Cash Flows [Abstract]
Cash flows from operating activities:
Net loss
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization
Stock-based compensation
Expense related to modification of warrants
Amortization of fair value of common stock issued for services
Fair value of common stock issued for product license and option
Amortization of fair value of warrants granted for services
Changes in operating assets and liabilities:
Receivable from supplier
Prepaid expenses and other current assets
Right of use asset - operating lease
Operating lease liability
Accounts payable and accrued expenses
Deferred rent
Net cash used in operating activities
Cash flows from investing activities:
Purchases of equipment
Construction of tenant improvements
Net cash used in investing activities
Cash flows from financing activities:
Net proceeds from issuance of common stock and warrants, including Units
Repayment of financing lease obligation
Repayment of notes payable
Net cash provided by financing activities
Net (decrease) increase in cash and cash equivalents
Cash and cash equivalents at beginning of period
Cash and cash equivalents at end of period
Supplemental disclosure of noncash activites:
Insurance premiums settled by issuing note payable
Accrued dividends on Series B Preferred
Balances at beginning
Balances at beginning (in shares)
Proceeds from sale of common stock and warrants for cash in private placement offerings
Proceeds from sale of common stock and warrants for cash in private placement offerings (in shares)
Proceeds from exercise of warrants
Proceeds from exercise of warrants (in shares)
Accrued dividends on Series B Preferred stock
Stock-based compensation expense
Fair value of common stock issued for services
Fair value of common stock issued for services (in shares)
Balances at end
Balances at end (in shares)
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Description of Business
Basis of Presentation
Accounting Policies [Abstract]
Summary of Significant Accounting Policies
Other Assets [Abstract]
Prepaid Expenses and Other Current Assets
Property, Plant and Equipment [Abstract]
Property and Equipment
Payables and Accruals [Abstract]
Accrued Expenses
Notes Payable [Abstract]
Notes Payable
Equity [Abstract]
Capital Stock
Related Party Transactions [Abstract]
Related Party Transactions
Commitments and Contingencies Disclosure [Abstract]
Commitments and Contingencies
Subsequent Events [Abstract]
Subsequent Events
Use of Estimates
Research and Development Expenses
Stock-Based Compensation
Fair Value per share
Leases, Right-of- Use Assets and Lease Liabilities
Comprehensive Loss
Loss per Common Share
Fair Value Measurements
Recent Accounting Pronouncements
Summary of stock-based compensation expense
Fair value assumptions
Schedule of potentially dilutive securities excluded from computation of earnings per share
Prepaid expenses
Property and equipment
Accrued expenses
Notes payable
Warrants outstanding
Summary of presentation of operating lease
Summary of operating lease costs
Summary of expected lease expense
Summary of future minimum lease payments
Other Lease disclosure
Supplemental disclosure of cash flow information
Accumulated deficit during its development stage
Nature of Expense [Axis]
Stock option expense
Fair Value Hierarchy and NAV [Axis]
Award Type [Axis]
Market price per share at grant date
Exercise price per share
Risk-free interest rate
Estimated term in years
Volatility
Dividend rate
Shares
Fair value per share
Antidilutive securities
AV-101 materials and services
Professional services
Insurance
Public offering filing fees and expenses
All other
Total
Property and equipment, gross
Accumulated depreciation and amortization
Property And Equipment Details 1
Office equipment subject to financing lease
Accumulated depreciation
Net book value of office equipment subject to financing lease
Accrued AV-101 development and related expenses
Accrued compensation
Accrued professional services
All other
Total
Principal balance
Accrued interest
Total
Class of Warrant or Right [Axis]
Warrant 7 [Member]
Warrant 8 [Member]
Statistical Measurement [Axis]
Exercise price per share
Weighted average price per share
Expiration date range
Warrants outstanding
Related Party [Axis]
Incurred expenses on research and subsequent other projects
Assets
Right of use asset operating lease
Liabilities
Current operating lease obligation
Non-current operating lease obligation
Total operating lease liability
Operating lease cost
Total lease expense
2021
2022
2023
2024
Thereafter
Total lease expense
Less imputed interest
Present value of operating lease liabilities
Commitments And Contingencies
Fiscal Years Ending March 31,
2020
2021
2022
2023
2024
Thereafter
Total
Assumed remaining lease term in years
Assumed discount rate
Cash paid for amounts included in the measurement of lease liabilities
Information about property i.e. tenant improvements.
Assets, Current
Assets
Liabilities, Current
Liabilities, Noncurrent
Liabilities [Default Label]
Treasury Stock, Value
Stockholders' Equity Attributable to Parent
Liabilities and Equity
Operating Expenses
Operating Income (Loss)
Income (Loss) from Continuing Operations before Equity Method Investments, Income Taxes, Noncontrolling Interest
Income Tax Expense (Benefit)
Preferred Stock Dividends and Other Adjustments
Dividends
Increase (Decrease) in Other Receivables
Increase (Decrease) in Prepaid Expense and Other Assets
Increase (Decrease) in Other Operating Assets
Net Cash Provided by (Used in) Operating Activities
Payments to Acquire Property, Plant, and Equipment
Payments for Capital Improvements
Net Cash Provided by (Used in) Investing Activities
Repayments of Long-term Capital Lease Obligations
Repayments of Notes Payable
Net Cash Provided by (Used in) Financing Activities
Cash and Cash Equivalents, Period Increase (Decrease)
Schedule of Accrued Liabilities [Table Text Block]
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment
Capital Leases, Lessee Balance Sheet, Assets by Major Class, Accumulated Depreciation
Other Accrued Liabilities, Current
Convertible Debt
Class of Warrant or Right, Exercise Price of Warrants or Rights
Class of Warrant or Right, Outstanding
Lessee, Operating Lease, Liability, Payments, Due
Lessee, Operating Lease, Liability, Undiscounted Excess Amount
Operating Leases, Future Minimum Payments, Remainder of Fiscal Year
Operating Leases, Future Minimum Payments, Due in Two Years
Operating Leases, Future Minimum Payments, Due in Four Years
Operating Leases, Future Minimum Payments, Due Thereafter
Operating Leases, Future Minimum Payments Due