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Research and Development Expenses (Details Narrative) - USD ($)
3 Months Ended 12 Months Ended
Mar. 31, 2019
Dec. 31, 2018
Sep. 30, 2018
Jun. 30, 2018
Mar. 31, 2018
Dec. 31, 2017
Sep. 30, 2017
Jun. 30, 2017
Mar. 31, 2019
Mar. 31, 2018
Research and Development [Abstract]                    
Research and development $ 3,758,000 $ 5,335,000 $ 5,261,000 $ 2,744,000 $ 2,638,000 $ 1,602,000 $ 2,427,000 $ 1,096,000 $ 17,098,500 $ 7,762,500