Business (Details)	Dec. 31, 2016 trial
Phase Three Trials Failure to Meet Primary Endpoint
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Number of trials completed	2
Phase Three Clinical Trial
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Number of trials completed	3

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

No definition available.

Name:	us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems
Namespace Prefix:	us-gaap_
Data Type:	xbrli:stringItemType
Balance Type:	na
Period Type:	duration