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Summary of Significant Accounting Policies (Tables)
3 Months Ended
Mar. 31, 2017
Accounting Policies [Abstract]  
Summary of the components of collaboration revenue
Below is a summary of the components of the Company’s collaboration revenue for the three months ended March 31, 2017 and 2016:
 
 
Three months ended March 31,
 
2017
 
2016
 
 
 
 
License revenue
$

 
$

Research and development activity revenue
1,658

 
1,275

API transfer revenue

 
14,443

Joint operating committee revenue
4

 
3

Total collaboration revenue
$
1,662

 
$
15,721

Schedule of share-based compensation expense
Share-based compensation expense includes expenses related to stock options and RSUs granted to employees, non-employee directors and consultants, as well as the option granted to employees to purchase shares under the ESPP, all of which have been reported in the Company’s Statements of Operations as follows:
 
 
Three months ended March 31,
 
2017
 
2016
 
 
 
 
Research and development
$
4,150

 
$
4,685

General and administrative
1,914

 
3,647

Total
$
6,064

 
$
8,332