Income Taxes (Tables)

12 Months Ended

Dec. 31, 2016

Income Tax Disclosure [Abstract]

Schedule of reconciliation of the statutory U.S. federal rate to the Company's effective tax rate

A reconciliation of the statutory U.S. federal rate to the Company's effective tax rate is as follows:

	Years ended December 31,
	2016		2015		2014
Percent of pre-tax income:
U.S. federal statutory income tax rate	35.0	%	35.0	%	35.0	%
State taxes, net of federal benefit	2.8	%	7.4	%	6.8	%
Permanent items	(1.4	)%	(0.5	)%	2.3	%
Impact of state rate changes	(11.0	)%	0.9	%	—	%
Research and development credit	1.9	%	—	%	—	%
Other	1.1	%	—	%	—	%
Change in valuation allowance	(28.2	)%	(29.1	)%	(89.5	)%
Effective income tax rate	0.2	%	13.7	%	(45.4	)%

Schedule of components of income tax (benefit) expense

The components of income tax (benefit) expense are as follows:

	Years ended December 31,
	2016			2015			2014
Current:
Federal	$	(23,393	)	$	136		$	29,505
State	21			91			11,440
Deferred:
Federal	22,966			(17,014		)	(4,469		)
State	—			—			—
Income tax (benefit) expense	$	(406	)	$	(16,787	)	$	36,476

Schedule of significant components of the Company's deferred tax assets (liabilities)

Significant components of the Company's deferred tax assets (liabilities) for 2016 and 2015 consist of the following:

	As of December 31,
	2016			2015
Deferred tax assets (liabilities)
Deferred revenue	$	125,634		$	142,675
License and technology payments	10,532			13,150
Share-based compensation	16,494			11,427
Accrued expenses	530			743
Depreciation	(651		)	(617		)
Federal and state net operating loss carryforwards	75,177			26,065
Excess tax benefits related to share-based compensation	—			1,630
Research and development credits	3,720			—
Other	2,155			5
Deferred income tax assets	233,591			195,078
Valuation allowance	(233,591		)	(171,965		)
Net deferred tax assets	$	—		$	23,113

Schedule of position with respect to uncertain tax positions

The Company's position with respect to uncertain tax positions is set forth below:

Opening balance	$	300
Gross amount of increases in unrecognized tax benefits during the period - current year provisions	—
Gross amount of increases in unrecognized tax benefits during the period - prior year provisions	3,828
Gross amount of increases in unrecognized tax benefits during the period - other	—
Decreases due to settlement with tax authorities during the period	—
Reduction of unrecognized tax benefits due to expiration of the state of limitations during the period	—
Closing Balance	$	4,128