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Licensing and Commercialization Agreement with Novartis Pharma AG (Tables)
12 Months Ended
Dec. 31, 2016
Organization, Consolidation and Presentation of Financial Statements [Abstract]  
Schedule of collaboration revenue components
Below is a summary of the components of the Company's collaboration revenue for the years ended December 31, 2016, 2015, and 2014:
 
Years ended December 31,
 
2016
 
2015
 
2014
License revenue
$
22,937

 
$
38,083

 
$
38,373

Research and development activity revenue
9,741

 
8,378

 
2,000

API transfer revenue
18,212

 
5,020

 
883

Joint operating committee revenue
19

 
24

 
3

Total collaboration revenue
$
50,909

 
$
51,505

 
$
41,259