Commitments and Contingencies - miniCEP290 Program - University of Massachusetts (Details) - University Of Massachusetts (UMass) - miniCEP290 - License Agreements - USD ($)	1 Months Ended		12 Months Ended
	Sep. 30, 2019	Jul. 31, 2019	Dec. 31, 2022
Schedule of Commitments and Contingencies [Line Items]
Shares issued for license fees (in shares)		75,000
Research and development
Schedule of Commitments and Contingencies [Line Items]
Payments for license fees	$ 400,000
Achievement of Specified Clinical and Regulatory Milestones | Research and development
Schedule of Commitments and Contingencies [Line Items]
Payments for license fees		$ 14,750,000	$ 14,750,000
Shares issued for license fees (in shares)		75,000	75,000
Specified Commercial Sales Milestones Related to a Licensed Product | Research and development
Schedule of Commitments and Contingencies [Line Items]
Payments for license fees		$ 48,000,000	$ 48,000,000