Commitments and Contingencies - Avacincaptad Pegol - Archemix Corp. (Details)		1 Months Ended			8 Months Ended	12 Months Ended
	Jun. 30, 2022 EUR (€)	Oct. 31, 2020 USD ($)	Mar. 31, 2020 USD ($)	Sep. 30, 2011 USD ($)	Oct. 31, 2020 USD ($)	Dec. 31, 2022 EUR (€)	Dec. 31, 2022 USD ($)
DelSiTech | Avacincaptad Pegol | License Agreements
Schedule of Commitments and Contingencies [Line Items]
Payments for license fees | €	€ 1,250,000
Achievement of Specified Clinical and Regulatory Milestones | Archemix | C5 Licensed Product | License Agreements
Schedule of Commitments and Contingencies [Line Items]
Amount to be paid on achievement of milestone							$ 50,500,000
Payments for license fees		$ 6,000,000	$ 1,000,000	$ 1,000,000	$ 9,000,000
Achievement of Specified Clinical and Regulatory Milestones | Archemix | C5 Licensed Product | Maximum | License Agreements
Schedule of Commitments and Contingencies [Line Items]
Amount to be paid on achievement of milestone				50,500,000
First Indication | Archemix | C5 Licensed Product | License Agreements
Schedule of Commitments and Contingencies [Line Items]
Amount to be paid on achievement of milestone				24,500,000			24,500,000
Second and Third Indication | Archemix | C5 Licensed Product | License Agreements
Schedule of Commitments and Contingencies [Line Items]
Amount to be paid on achievement of milestone				23,500,000			23,500,000
Sustained Delivery Applications | Archemix | C5 Licensed Product | License Agreements
Schedule of Commitments and Contingencies [Line Items]
Amount to be paid on achievement of milestone				2,500,000			2,500,000
Achievement of Specified Commercial Milestones | Archemix | C5 Licensed Product | License Agreements
Schedule of Commitments and Contingencies [Line Items]
Amount to be paid on achievement of milestone							$ 22,500,000
Achievement of Specified Commercial Milestones | Archemix | C5 Licensed Product | Maximum | License Agreements
Schedule of Commitments and Contingencies [Line Items]
Amount to be paid on achievement of milestone				$ 22,500,000
Achievement Of Specified Clinical And Development Milestones | DelSiTech | Avacincaptad Pegol | License Agreements
Schedule of Commitments and Contingencies [Line Items]
Amount to be paid on achievement of milestone | €	35,000,000
Achievement Of Specified Commercial Sales Milestones | DelSiTech | Avacincaptad Pegol | License Agreements
Schedule of Commitments and Contingencies [Line Items]
Payments for license fees | €	€ 60,000,000					€ 60,000,000