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Property and Equipment (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Property and Equipment      
Property and equipment, gross $ 980 $ 1,345  
Accumulated depreciation (807) (1,010)  
Property and equipment, net 173 335  
Depreciation expense $ 162 183 $ 2,763
Minimum      
Property and Equipment      
Useful life 3 years    
Maximum      
Property and Equipment      
Useful life 10 years    
Manufacturing and clinical equipment      
Property and Equipment      
Property and equipment, gross $ 47 412  
Manufacturing and clinical equipment | Minimum      
Property and Equipment      
Useful life 7 years    
Manufacturing and clinical equipment | Maximum      
Property and Equipment      
Useful life 10 years    
Computer, software and other office equipment      
Property and Equipment      
Useful life 5 years    
Property and equipment, gross $ 933 $ 933