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Licensing and Commercialization Agreement (Tables)
12 Months Ended
Dec. 31, 2018
Organization, Consolidation and Presentation of Financial Statements [Abstract]  
Schedule of collaboration revenue components
Below is a summary of the components of the Company's collaboration revenue for the years ended December 31, 2018, 2017, and 2016:
 
Years ended December 31,
 
2018
 
2017
 
2016
License revenue
$

 
$
152,912

 
$
22,937

Research and development activity revenue

 
56,180

 
9,741

API transfer revenue

 
754

 
18,212

Joint operating committee revenue

 
131

 
19

Total collaboration revenue
$

 
$
209,977

 
$
50,909