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Stock Option and Compensation Plans - Summary of Stock Option Activity (Details)
shares in Thousands
6 Months Ended
Jun. 30, 2017
$ / shares
shares
Common Stock Options  
Outstanding, beginning of period (in shares) | shares 3,359
Granted (in shares) | shares 1,231
Exercised (in shares) | shares (20)
Expired or forfeited (in shares) | shares (765)
Outstanding, end of period (in shares) | shares 3,805
Weighted Average Exercise Price  
Outstanding, beginning of period (in dollars per share) | $ / shares $ 39.92
Granted (in dollars per share) | $ / shares 4.33
Exercised (in dollars per share) | $ / shares 1.64
Expired or forfeited (in dollars per share) | $ / shares 41.96
Outstanding, end of period (in dollars per share) | $ / shares $ 28.18
Options exercisable at end of period (in shares) | shares 1,831
Weighted average grant date fair value (per share) of options granted during the period (in dollars per share) | $ / shares $ 3.00