Business (Details)	6 Months Ended
	Jun. 30, 2017 candidate	Dec. 31, 2016 trial
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Number of product candidates | candidate	2
Phase Three Trials Failure to Meet Primary Endpoint
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Number of trials completed		2
Phase Three Clinical Trial
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Number of trials completed		3