Summary of Significant Accounting Policies (Tables)

6 Months Ended

Jun. 30, 2017

Summary of the components of collaboration revenue

Below is a summary of the components of the Company’s collaboration revenue for the three and six months ended June 30, 2017 and 2016:



	Three months ended June 30,				Six months ended June 30,
	2017		2016		2017		2016

License revenue	$	—	$	22,937	$	—	$	22,937
Research and development activity revenue	1,658		5,150		3,316		6,425
API transfer revenue	—		102		—		14,545
Joint operating committee revenue	3		9		7		12
Total collaboration revenue	$	1,661	$	28,198	$	3,323	$	43,919

Schedule of share-based compensation expense

Share-based compensation expense includes expenses related to stock options and RSUs granted to employees, non-employee directors and consultants, as well as the option granted to employees to purchase shares under the ESPP, all of which have been reported in the Company’s Statements of Operations as follows:



	Three months ended June 30,				Six months ended June 30,
	2017		2016		2017		2016

Research and development	$	2,897	$	6,383	$	7,047	$	11,068
General and administrative	2,091		1,926		4,005		5,573
Total	$	4,988	$	8,309	$	11,052	$	16,641