X0306 4 2017-12-29 0 0001410939 Ophthotech Corp. OPHT 0001277476 GUYER DAVID R C/O OPHTHOTECH CORPORATION ONE PENN PLAZA, 35TH FLOOR NEW YORK NY 10119 1 1 0 0 Executive Chairman Common Stock 2017-12-29 4 M 0 30480 A 50494 D Common Stock 2018-01-02 4 S 0 16520 3.19 D 33974 D Restricted Stock Units 2017-12-29 4 M 0 30480 0.00 D 2027-01-16 Common Stock 30480 0 D Restricted stock units converted into common stock on a one-for-one basis upon vesting of the units. Represents shares automatically sold pursuant to the prespecified terms of the applicable Restricted Stock Unit Agreement to satisfy the reporting person's minimum statutory withholding obligations with respect to the income recognized by the reporting person upon the vesting of the restricted stock units on December 29, 2017. These shares were disposed of in multiple transactions on January 2, 2018 at actual sales prices ranging from $3.10 to $3.25 per share. The price reported reflects the weighted average sale price for the transactions. The reporting person undertakes to provide upon request by the staff of the Securities Exchange Commission, the issuer or a security holder of the issuer, full information regarding the number of shares sold at each separate price. On January 17, 2017, the reporting person was granted an award of 60,960 restricted stock units, which vested with respect to 50% of the shares subject to the award on each of June 30, 2017 and December 29, 2017, subject to continued employment with the issuer and the other terms and conditions under the issuer's 2013 Stock Incentive Plan. /s/ David F. Carroll, as Attorney-in-Fact for David R. Guyer 2018-01-03