X0306 4 2016-09-29 0 0001410939 Ophthotech Corp. OPHT 0001277966 PATEL SAMIR CHANDRAKANT C/O OPHTHOTECH CORPORATION ONE PENN PLAZA, 19TH FLOOR NEW YORK NY 10119 1 1 0 0 President Common Stock 2016-09-29 4 S 0 7292 54.13 D 24239 D Common Stock 2016-09-29 4 S 0 2612 54.93 D 21627 D Common Stock 2016-09-29 4 S 0 8096 55.75 D 13531 D Common Stock 2016-09-29 4 S 0 2000 56.90 D 11531 D The sales reported on this form were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 4, 2015. These shares were disposed of in multiple transactions on September 29, 2016 at actual sales prices ranging from $53.47 to $54.46 per share. The price reported reflects the weighted average sale price for the transactions. The reporting person undertakes to provide upon request by the staff of the Securities Exchange Commission, the issuer or a security holder of the issuer, full information regarding the number of shares sold at each separate price. These shares were disposed of in multiple transactions on September 29, 2016 at actual sales prices ranging from $54.47 to $55.46 per share. The price reported reflects the weighted average sale price for the transactions. The reporting person undertakes to provide upon request by the staff of the Securities Exchange Commission, the issuer or a security holder of the issuer, full information regarding the number of shares sold at each separate price. These shares were disposed of in multiple transactions on September 29, 2016 at actual sales prices ranging from $55.47 to $56.23 per share. The price reported reflects the weighted average sale price for the transactions. The reporting person undertakes to provide upon request by the staff of the Securities Exchange Commission, the issuer or a security holder of the issuer, full information regarding the number of shares sold at each separate price. These shares were disposed of in multiple transactions on September 29, 2016 at actual sales prices ranging from $56.61 to $57.53 per share. The price reported reflects the weighted average sale price for the transactions. The reporting person undertakes to provide upon request by the staff of the Securities Exchange Commission, the issuer or a security holder of the issuer, full information regarding the number of shares sold at each separate price. /s/ Justin Vogel, as Attorney-in-Fact for Samir Patel 2016-10-03