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Royalty Agreement and Series C Agreement (Details 2) (USD $)
12 Months Ended 84 Months Ended 0 Months Ended 1 Months Ended
Dec. 31, 2013
Dec. 31, 2011
Dec. 31, 2013
May 23, 2013
Series C Agreement
Series C Preferred Stock
Aug. 31, 2013
Series C Agreement
Series C Preferred Stock
Aug. 07, 2013
Series C Agreement
Series C Preferred Stock
May 31, 2013
Series C Agreement
Series C Preferred Stock
May 23, 2013
Series C Agreement
Common stock
May 23, 2013
Initial Public Offering
Common stock
Conversion Terms
Series C Preferred Stock Purchase Agreement                  
Shares available for sale and issuance under agreement             20,000,000    
Share price (in dollars per share)           $ 2.50 $ 2.50   $ 14.75
Share price on a post-reverse stock split basis (in dollars per share)           $ 14.75 $ 14.75    
Shares issued           13,333,333 6,666,667    
Share price at fair value (in dollars per share)       $ 2.50       $ 10.03  
Common stock conversion price (in dollars per share)       $ 14.75          
Conversion ratio (per share of common stock)               1  
Beneficial conversion feature       $ 0          
Aggregate proceeds $ 49,699,000 $ 14,990,000 $ 130,632,000   $ 33,300,000