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Selected Quarterly Financial Information (unaudited) (Tables)
 12 Months Ended
Dec. 31, 2013
Selected Quarterly Financial Information (unaudited)  
Summary of the quarterly results of operations

 

 
   2013  
 
   March 31   June 30   September 30   December 31  

Revenues

   $ —   $ —   $ —   $ —  

Research and development

     2,390     4,345     11,101     15,379  

General and administrative

     1,738     3,241     4,166     5,065  
                   
​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​

Loss from operations

     (4,128 )   (7,586 )   (15,267 )   (20,444 )

Net loss attributable to common shareholders

   $ (6,361 ) $ (11,863 ) $ (18,424 ) $ (20,388 )

Basic and diluted earnings per common share

   $ (4.33 ) $ (8.07 ) $ (10.26 ) $ (0.65 )


 

 
   2012  
 
   March 31   June 30   September 30   December 31  

Revenues

   $ —   $ —   $ —   $ —  

Research and development

     1,621     1,578     1,595     1,998  

General and administrative

     1,388     1,694     2,259     1,548  
                   
​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​ ​

Loss from operations

     (3,009 )   (3,272 )   (3,854 )   (3,546 )

Net loss attributable to common shareholders

   $ (4,765 ) $ (5,326 ) $ (5,928 ) $ (5,606 )

Basic and diluted earnings per common share

   $ (3.31 ) $ (3.68 ) $ (4.07 ) $ (3.81 )