Note 15 - Stockholders' Equity (Deficit) (Details Textual)										1 Months Ended			3 Months Ended		12 Months Ended	17 Months Ended	24 Months Ended
	Feb. 27, 2024 USD ($) $ / shares shares	Oct. 20, 2023 USD ($) shares	Oct. 04, 2023 $ / shares shares	Sep. 08, 2023 USD ($) shares	Jul. 12, 2023 USD ($) shares	May 15, 2023 USD ($) shares	May 11, 2023	May 10, 2023	Jul. 12, 2022 USD ($) $ / shares shares	Nov. 30, 2022 USD ($) $ / shares shares	Nov. 30, 2017	Nov. 30, 2010	Mar. 31, 2024 USD ($) $ / shares shares	Mar. 31, 2023 USD ($) $ / shares shares	Dec. 31, 2022 USD ($) shares	Dec. 31, 2023 USD ($) $ / shares shares	Jun. 30, 2022 USD ($) $ / shares shares	May 31, 2023 USD ($) $ / shares	Jun. 16, 2020 USD ($) $ / shares shares
Common Stock, Par or Stated Value Per Share (in dollars per share) | $ / shares													$ 0.0001			$ 0.0001
Proceeds from Issuance of Common Stock | $													$ 10,000	$ 803,000
Common Stock, Capital Shares Reserved for Future Issuance (in shares)													21,975,516			18,887,958
Share-based Compensation Arrangement by Share-based Payment Award, Fair Value Assumptions, Expected Dividend Payments | $													$ 0
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period, Intrinsic Value | $													$ 0	$ 0
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value (in dollars per share) | $ / shares													$ 0.705	$ 2.82
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested in Period, Fair Value | $													$ 355,000	$ 346,000
The 2010 Share Option Plan [Member]
Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Period (Year)											10 years	7 years
Common Stock, Capital Shares Reserved for Future Issuance (in shares)													10,061			28,168
The 2019 Plan [Member]
Common Stock, Capital Shares Reserved for Future Issuance (in shares)													244,180			71,412
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Authorized (in shares)													30,000
Share-based Compensation Arrangement by Share-based Payment Award, Increase in Authorized Shares, Percentage of Outstanding Stock Maximum													4.00%
The 2024 Investor Warrants [Member]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares)	817,748
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) | $ / shares	$ 1.34
Voting Preferred Stock [Member]
Preferred Stock, Liquidation Preference Per Share (in dollars per share) | $ / shares										$ 30
Preferred Stock, Convertible, Conversion Ratio										0.6667
Preferred Stock, Convertible, Volume Weighted Average Price Per Common Share (in dollars per share) | $ / shares										$ 18.75
Senior Preferred Stock [Member]
Preferred Stock, Convertible, Conversion Ratio						2.6667
Liquidation Preference, Multiplier						2.5
Conversion Price, Benchmark, Multiplier						2.75
Series X Convertible Preferred Stock [Member][
Shares Issued, Price Per Share (in dollars per share) | $ / shares			$ 20.1
Preferred Stock, Par or Stated Value Per Share (in dollars per share) | $ / shares			$ 0.0001
Preferred Stock, Convertible, Conversion Ratio			10
Preferred Stock, Shares Authorized (in shares)			400,000
Preferred Stock, Dividend Rate, Percentage			12.50%
Common Stock [Member]
Stock Issued During Period, Shares, New Issues (in shares)													8,333	224,378
H.C. Wainwright & Co., LLC [Member] | Placement Agent Warrants [Member]
Class of Warrant or Right, Number of Securities Called by Warrants or Rights (in shares)	57,242
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) | $ / shares	$ 1.8313
Equity Purchase Agreement [Member] | Lincoln Park [Member]
Equity Purchase Agreement, Maximum Offering Amount | $																			$ 31,000,000
Common Stock, Par or Stated Value Per Share (in dollars per share) | $ / shares																			$ 0.0001
Equity Purchase Agreement, Maximum Shares Issuable (in shares)																			517,560
Equity Agreement, Maximum Percentage of Stock Outstanding																			19.99%
Equity Agreement, Minimum Average Purchase Price (in dollars per share) | $ / shares																			$ 59.6325
Maximum Percentage of Outstanding Stock, Beneficial Ownership																			9.99%
Stock Issued During Period, Shares, New Issues (in shares)															26,666,000		229,139
Shares Issued, Price Per Share (in dollars per share) | $ / shares																	$ 40.5
Stock Issued During Period, Shares, Commitment Fee (in shares)																	13,971
Stock Issued During Period, Value, Commitment Fee | $																	$ 620,000
Deferred Offering Costs | $															$ 0		$ 123,000
Proceeds from Issuance of Common Stock | $															$ 272,000
LPC Purchase Agreement 2022 [Member] | Lincoln Park [Member]
Equity Purchase Agreement, Maximum Offering Amount | $									$ 11,000,000
Common Stock, Par or Stated Value Per Share (in dollars per share) | $ / shares									$ 0.0001
Equity Purchase Agreement, Maximum Shares Issuable (in shares)									858,224
Equity Agreement, Maximum Percentage of Stock Outstanding									19.99%
Maximum Percentage of Outstanding Stock, Beneficial Ownership									9.99%
Shares Issued, Price Per Share (in dollars per share) | $ / shares													$ 1.16			$ 3.966
Stock Issued During Period, Shares, Commitment Fee (in shares)									45,701				8,333			776,452
Stock Issued During Period, Value, Commitment Fee | $									$ 330,000				$ 10,000			$ 3,080,000
The 2022 Private Placement [Member]
Proceeds from Issuance of Private Placement | $										$ 6,720,000
Payments of Stock Issuance Costs | $										$ 202,000
The 2022 Private Placement [Member] | Convertible Preferred Stock [Member]
Stock Issued During Period, Shares, New Issues (in shares)										3,185,000
Preferred Stock, Par or Stated Value Per Share (in dollars per share) | $ / shares										$ 0.0001
Preferred Stock, Convertible, Shares Issuable (in shares)										2,123,443
The 2022 Private Placement [Member] | Common Stock [Member]
Common Stock, Par or Stated Value Per Share (in dollars per share) | $ / shares										$ 0.0001
Stock Issued During Period, Shares, New Issues (in shares)										116,668
Multi-Tranche Private Placement 2023 [Member]
Equity Purchase Agreement, Maximum Offering Amount | $																		$ 9,000,000
Equity Purchase Agreement, Minimum Aggregate Purchase Amount Per Tranche | $																		$ 500,000
Multi-Tranche Private Placement 2023 [Member] | Senior Preferred Stock [Member]
Stock Issued During Period, Shares, New Issues (in shares)		502,513		292,398	500,000	280,899
Preferred Stock, Par or Stated Value Per Share (in dollars per share) | $ / shares																		$ 0.0001
Proceeds from Issuance of Preferred Stock and Preference Stock | $		$ 2,000,000		$ 1,000,000	$ 2,000,000	$ 2,000,000
Registered Direct Offering [Member]
Maximum Percentage of Outstanding Stock, Beneficial Ownership	4.99%
Stock Issued During Period, Shares, New Issues (in shares)	817,748
Shares Issued, Price Per Share (in dollars per share) | $ / shares	$ 1.465
Proceeds from Issuance or Sale of Equity | $	$ 1,200,000
Registered Direct Offering [Member] | H.C. Wainwright & Co., LLC [Member]
Placement Agent Fee, Percentage of Gross Proceeds	7.00%
Management Fee, Percentage of Gross Proceeds	1.00%
Maximum [Member] | Registered Direct Offering [Member]
Maximum Percentage of Outstanding Stock, Beneficial Ownership	9.99%
Reverse Stock Split [Member]
Stockholders' Equity Note, Stock Split, Conversion Ratio							15
Reverse Stock Split [Member] | Minimum [Member]
Stockholders' Equity Note, Stock Split, Conversion Ratio								5
Reverse Stock Split [Member] | Maximum [Member]
Stockholders' Equity Note, Stock Split, Conversion Ratio								15