Note 14 - Stockholders Equity - Stock Options Outstanding and Exercisable (Details)	12 Months Ended
	Dec. 31, 2023 $ / shares shares
Options outstanding, number (in shares) | shares	981,834
Options outstanding, weighted average remaining contractual term (Year)	7 years 6 months 29 days
Options outstanding, weighted average exercise price (in dollars per share)	$ 19.85
Options exercisable (in shares) | shares	396,267
Options exercisable, weighted average remaining contractual term (Year)	6 years 2 months 26 days
Options exercisable, weighted average exercise price (in dollars per share)	$ 36.44
Range One [Member]
Options outstanding, number (in shares) | shares	933,055
Exercise price range, lower limit (in dollars per share)	$ 1.9
Exercise price range, upper limit (in dollars per share)	$ 54.6
Options outstanding, weighted average remaining contractual term (Year)	7 years 9 months 14 days
Options outstanding, weighted average exercise price (in dollars per share)	$ 14.9
Options exercisable (in shares) | shares	348,118
Options exercisable, weighted average remaining contractual term (Year)	6 years 7 months 17 days
Options exercisable, weighted average exercise price (in dollars per share)	$ 25.59
Range Two [Member]
Options outstanding, number (in shares) | shares	46,063
Exercise price range, lower limit (in dollars per share)	$ 63.9
Exercise price range, upper limit (in dollars per share)	$ 119.25
Options outstanding, weighted average remaining contractual term (Year)	3 years 5 months 8 days
Options outstanding, weighted average exercise price (in dollars per share)	$ 99.31
Options exercisable (in shares) | shares	45,433
Options exercisable, weighted average remaining contractual term (Year)	3 years 4 months 28 days
Options exercisable, weighted average exercise price (in dollars per share)	$ 99.44
Range Three [Member]
Options outstanding, number (in shares) | shares	1,627
Exercise price range, lower limit (in dollars per share)	$ 186.75
Exercise price range, upper limit (in dollars per share)	$ 382.5
Options outstanding, weighted average remaining contractual term (Year)	4 years 8 months 26 days
Options outstanding, weighted average exercise price (in dollars per share)	$ 271.15
Options exercisable (in shares) | shares	1,627
Options exercisable, weighted average remaining contractual term (Year)	4 years 8 months 26 days
Options exercisable, weighted average exercise price (in dollars per share)	$ 271.15
Range Four [Member]
Options outstanding, number (in shares) | shares	637
Exercise price range, lower limit (in dollars per share)	$ 405
Exercise price range, upper limit (in dollars per share)	$ 438.75
Options outstanding, weighted average remaining contractual term (Year)	8 months 19 days
Options outstanding, weighted average exercise price (in dollars per share)	$ 405.21
Options exercisable (in shares) | shares	637
Options exercisable, weighted average remaining contractual term (Year)	8 months 19 days
Options exercisable, weighted average exercise price (in dollars per share)	$ 405.21
Range Five [Member]
Options outstanding, number (in shares) | shares	452
Exercise price range, lower limit (in dollars per share)	$ 650.25
Exercise price range, upper limit (in dollars per share)	$ 958.5
Options outstanding, weighted average remaining contractual term (Year)	2 years 8 months 4 days
Options outstanding, weighted average exercise price (in dollars per share)	$ 696.15
Options exercisable (in shares) | shares	452
Options exercisable, weighted average remaining contractual term (Year)	2 years 8 months 4 days
Options exercisable, weighted average exercise price (in dollars per share)	$ 696.15