Note 14 - Stockholders Equity - Stock Option Activity (Details) - USD ($) $ / shares in Units, $ in Thousands	12 Months Ended
	Dec. 31, 2023	Dec. 31, 2022
Outstanding, number of shares (in shares)	849,613
Outstanding, weighted average exercise price (in dollars per share)	$ 25.05
Outstanding, weighted average remaining contractual term (Year)	7 years 6 months 29 days	8 years 2 months 23 days
Outstanding, aggregate intrinsic value	$ 0	$ 209
Options granted, number of shares (in shares)	229,531
Options granted, weighted average exercise price (in dollars per share)	$ 2.81
Options granted, aggregate intrinsic value	$ 0
Options exercised, number of shares (in shares)	0
Options exercised, weighted average exercise price (in dollars per share)	$ 0
Options exercised, aggregate intrinsic value	$ 0	$ 0
Options forfeited/cancelled, number of shares (in shares)	(97,310)
Options forfeited/cancelled, weighted average exercise price (in dollars per share)	$ 25.37
Options forfeited/cancelled, aggregate intrinsic value (in dollars per share)	$ 0
Outstanding, number of shares (in shares)	981,834	849,613
Outstanding, weighted average exercise price (in dollars per share)	$ 19.85	$ 25.05
Exercisable, number of shares (in shares)	396,267
Exercisable, weighted average exercise price (in dollars per share)	$ 36.44
Exercisable, weighted average remaining contractual term (Year)	6 years 2 months 26 days
Exercisable, aggregate intrinsic value	$ 0
Expected to vest, number of shares (in shares)	585,567
Expected to vest, weighted average exercise price (in dollars per share)	$ 8.62
Expected to vest, weighted average remaining contractual term (Year)	8 years 5 months 23 days
Expected to vest, aggregate intrinsic value	$ 0