Note 15 - Common Stock Reserved for Issuance

12 Months Ended

Dec. 31, 2022

Notes to Financial Statements

Common Stock Reserved For Issuance [Text Block]

15. COMMON STOCK RESERVED FOR ISSUANCE

The Company is required to reserve and keep available out of its authorized but unissued shares of common stock a number of shares sufficient to affect the exercise of all options granted and available for grant under the incentive plans and warrants to purchase common stock.

	December 31, 2022		December 31, 2021
Outstanding common stock warrants		15,928,867		15,928,867
Outstanding stock options and RSUs		13,130,144		5,977,179
Preferred shares		31,850,000		3,790,755
Shares reserved for conversion of future non-voting preferred share issuance		1,209,245		1,209,245
Shares reserved for conversion of future voting preferred share issuance		9,150,000		—
Shares reserved for future option grants and RSUs		376,201		589,064
Shares reserved for Lincoln Park		15,814,471		5,222,867
Shares reserved for Madryn Noteholders		8,215,706		8,213,880
Total common stock reserved for issuance		95,674,634		40,931,857