Note 13 - Common Stock Reserved for Issuance (Tables)

3 Months Ended

Mar. 31, 2022

Notes Tables

Schedule of Common Stock Reserved for Issuance [Table Text Block]

	March 31, 2022		December 31, 2021
Outstanding common stock warrants		15,928,867		15,928,867
Outstanding stock options and RSUs		7,878,714		5,977,179
Preferred shares		3,790,755		3,790,755
Shares reserved for conversion of future preferred share issuance		1,209,245		1,209,245
Shares reserved for future option grants and RSUs		1,230,036		589,064
Shares reserved for Lincoln Park		5,222,867		5,222,867
Shares reserved for Madryn Noteholders		8,213,880		8,213,880
Total common stock reserved for issuance		43,474,364		40,931,857