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Share Based Compensation (Details) - USD ($)
$ in Millions
12 Months Ended
Jan. 01, 2024
Dec. 31, 2024
Dec. 31, 2023
2019 Plan      
Share-based compensation      
Percentage of shares reserved for future issuance 1339324.00%    
Shares reserved for issuance   9,522,270  
Number of options forfeited after termination of one plan 125,323    
Shares available for future grants   922,575  
Cancelled   561,000 561,000
2021 Inducement Plan      
Share-based compensation      
Shares reserved for issuance   1,000,000  
Shares available for future grants   504,000  
Employee Stock Option      
Share-based compensation      
Original grant-date fair value   $ 2.1 $ 5.5
Employee Stock Option | 2011 Plan      
Share-based compensation      
Vesting period   4 years  
Employee Stock Option | 2011 Plan | Share-based Compensation Award, Tranche One      
Share-based compensation      
Percentage of shares to vest   25.00%  
Employee Stock Option | 2011 Plan | Share-based Compensation Award, Tranche Two      
Share-based compensation      
Percentage of shares to vest   2.78%  
Employee Stock Option | 2019 Plan      
Share-based compensation      
Vesting period   4 years  
Employee Stock Option | 2019 Plan | Share-based Compensation Award, Tranche One      
Share-based compensation      
Percentage of shares to vest   25.00%  
Employee Stock Option | 2019 Plan | Share-based Compensation Award, Tranche Two      
Share-based compensation      
Percentage of shares to vest   2.78%