Condensed Consolidated Statements of Shareholders' Equity - USD ($) $ in Thousands	Common Shares	Pre-funded warrants	Additional paid-in capital	Accumulated deficit	Total
Opening balance at Dec. 31, 2022	$ 273,900	$ 34,352	$ 24,437	$ (266,341)	$ 66,348
Beginning Balance (in shares) at Dec. 31, 2022	34,286,002	8,518,257
Increase (Decrease) in Stockholders' Equity
Net loss				(46,074)	(46,074)
Exercise of stock options	$ 324		(136)		188
Exercise of stock options (in shares)	112,779
Pre-funded warrants - Private Placement, net of issuance costs		$ 14,107			14,107
Pre-funded warrants - Private Placement, net of issuance costs (in shares)		1,059,000
Share-based compensation			7,657		7,657
Exchange of common shares	$ (14,115)				(14,115)
Exchange of common shares (in shares)	(1,059,000)
Employee stock purchase plan purchases	$ 393				393
Employee stock purchase plan purchases (in shares)	142,006
Closing balance at Sep. 30, 2023	$ 260,502	$ 48,459	31,958	(312,415)	28,504
Ending Balance (in shares) at Sep. 30, 2023	33,481,787	9,577,257
Opening balance at Jun. 30, 2023	$ 260,169	$ 48,459	29,114	(297,334)	40,408
Beginning Balance (in shares) at Jun. 30, 2023	33,363,971	9,577,257
Increase (Decrease) in Stockholders' Equity
Net loss				(15,081)	(15,081)
Exercise of stock options	$ 68		(28)		40
Exercise of stock options (in shares)	18,798
Share-based compensation			2,872		2,872
Employee stock purchase plan purchases	$ 265				265
Employee stock purchase plan purchases (in shares)	99,018
Closing balance at Sep. 30, 2023	$ 260,502	$ 48,459	31,958	(312,415)	28,504
Ending Balance (in shares) at Sep. 30, 2023	33,481,787	9,577,257
Opening balance at Dec. 31, 2023	$ 260,504	$ 48,459	33,834	(326,026)	$ 16,771
Beginning Balance (in shares) at Dec. 31, 2023	33,483,111	9,577,257			33,483,111
Increase (Decrease) in Stockholders' Equity
Net loss				(29,156)	$ (29,156)
Exercise of stock options	$ 53		(24)		29
Exercise of stock options (in shares)	24,400
Pre-funded warrants - Private Placement, net of issuance costs		$ 4,617			4,617
Pre-funded warrants - Private Placement, net of issuance costs (in shares)		3,333,333
Share-based compensation			4,302		4,302
Issuance of common shares, net of issuance costs	$ 27,258				27,258
Issuance of common shares, net of issuance costs (shares)	19,666,667
Employee stock purchase plan purchases	$ 191				191
Employee stock purchase plan purchases (in shares)	153,730
Closing balance at Sep. 30, 2024	$ 288,006	$ 53,076	38,112	(355,182)	$ 24,012
Ending Balance (in shares) at Sep. 30, 2024	53,327,908	12,910,590			53,327,908
Opening balance at Jun. 30, 2024	$ 287,932	$ 53,076	36,713	(345,743)	$ 31,978
Beginning Balance (in shares) at Jun. 30, 2024	53,269,565	12,910,590
Increase (Decrease) in Stockholders' Equity
Net loss				(9,439)	(9,439)
Share-based compensation			1,399		1,399
Employee stock purchase plan purchases	$ 74				74
Employee stock purchase plan purchases (in shares)	58,343
Closing balance at Sep. 30, 2024	$ 288,006	$ 53,076	$ 38,112	$ (355,182)	$ 24,012
Ending Balance (in shares) at Sep. 30, 2024	53,327,908	12,910,590			53,327,908