Share Based Compensation - Non-vested share options (Details) - $ / shares		9 Months Ended
	Feb. 16, 2022	Sep. 30, 2022	Sep. 30, 2021
Plans 2011 and 2019 and 2021 Inducement [Member]
Number of options
Non-vested share options at end of period		3,809,126	3,092,061
Weighted average fair value
Non-vested at end of period		$ 5.34	$ 6.07
2011 Plan
Number of options
Non-vested at beginning of period		200,639	543,192
Vested, outstanding		(170,883)	(267,789)
Non-vested share options at end of period		29,756	275,403
Weighted average fair value
Non-vested at beginning of period		$ 1.86	$ 1.81
Vested, outstanding		1.76	1.64
Non-vested at end of period		$ 2.44	$ 1.98
2019 Plan
Number of options
Non-vested at beginning of period		2,665,518	1,438,026
Granted		1,748,700	2,065,200
Vested, outstanding			(672,686)
Forfeited			(13,882)
Non-vested share options at end of period		3,256,370	2,816,658
Weighted average fair value
Non-vested at beginning of period		$ 6.39	$ 10.28
Granted		4.37	4.71
Vested, outstanding			9.17
Forfeited/expired			9.18
Non-vested at end of period		$ 5.45	$ 6.47
2021 Inducement Plan
Number of options
Granted		523,000
Vested, outstanding		(1,149,117)
Forfeited		(8,731)
Non-vested share options at end of period		523,000
Weighted average fair value
Granted	$ 4.81	$ 4.81
Vested, outstanding		5.99
Forfeited/expired		$ 6.27