Condensed Consolidated Statements of Cash Flows - USD ($) $ in Thousands	6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021
Cash flows used in operating activities
Net loss	$ (30,655)	$ (11,744)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation of property and equipment	47	46
Share-based compensation expense	4,525	3,280
Changes in operating assets and liabilities:
Other receivables	(134)	(19)
Research and development tax credits receivable	(183)	(178)
Prepaid expenses	834	(2,019)
Operating lease assets and liabilities	(4)	24
Accounts payable and accrued liabilities	(2,464)	(845)
Net cash used in operating activities	(28,034)	(11,455)
Cash provided by (used in) investing activities
Acquisition of property and equipment	(59)
Acquisition of short-term investments	(23,000)
Redemption of short-term investments		32,000
Net cash provided by (used in) investing activities	(23,059)	32,000
Cash provided by financing activities
Proceeds from exercise of options	189	19
Net Proceeds from issuance of pre-funded warrants in a private placement		4,920
Cash provided by financing activities	189	4,939
Net decrease in cash and cash equivalents	(50,904)	25,484
Cash and cash equivalents - Beginning of period	114,141	72,310
Cash and cash equivalents - End of period	$ 63,237	$ 97,794