Consolidated Statements of Shareholders Equity - USD ($) $ in Thousands	Common Shares	Pre-funded warrants	Additional paid-in capital	Cumulative translation adjustment	Accumulated deficit	Total
Beginning balance at Dec. 31, 2019	$ 226,245		$ 3,805	$ (1,634)	$ (113,499)	$ 114,917
Balance at the beginning of period (in shares) at Dec. 31, 2019	24,505,748
Increase (Decrease) in Stockholders' Equity and Temporary Equity
Net income (loss)					(49,967)	(49,967)
Exercise of stock options (note 7)	$ 520		(220)			300
Exercise of stock options (note 7) (in shares)	226,352
Share-based compensation (note 7)			4,945			4,945
Stock offering	$ 24,917	$ 23,236				48,153
Stock offering (in shares)	5,095,897	4,761,903
Private placement (note 7)		$ 24,771				24,771
Private placement (note 7) (in shares)		6,655,131
Ending balance at Dec. 31, 2020	$ 251,682	$ 48,007	8,530	(1,634)	(163,466)	$ 143,119
Balance at the end of period (in shares) at Dec. 31, 2020	29,827,997	11,417,034				29,827,997
Increase (Decrease) in Stockholders' Equity and Temporary Equity
Number of warrants						11,417,034
Net income (loss)					(42,853)	$ (42,853)
Exercise of stock options (note 7)	$ 219		(98)			121
Exercise of stock options (note 7) (in shares)	69,562
Share-based compensation (note 7)			7,279			7,279
Private placement (note 7)		$ 4,934				4,934
Private placement (note 7) (in shares)		910,746
Ending balance at Dec. 31, 2021	$ 251,901	$ 52,941	$ 15,711	$ (1,634)	$ (206,319)	$ 112,600
Balance at the end of period (in shares) at Dec. 31, 2021	29,897,559	12,327,780				29,897,559
Increase (Decrease) in Stockholders' Equity and Temporary Equity
Number of warrants						12,327,780