Shareholders’ equity (deficit) - Share-based compensation - Recognized share-based compensation expense (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2019	Sep. 30, 2018	Sep. 30, 2019	Sep. 30, 2018
Share-based compensation
Share-based compensation expense	$ 350	$ 85	$ 837	$ 289
Administration
Share-based compensation
Share-based compensation expense	194	22	396	72
Research and development
Share-based compensation
Share-based compensation expense	124	53	358	178
Commercial activities
Share-based compensation
Share-based compensation expense	$ 32	$ 10	$ 83	$ 39