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Income Taxes - Additional Information (Details) - USD ($)
12 Months Ended
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
Income Tax Contingency [Line Items]      
Effective tax rate 0.00% 0.00%  
Valuation allowance $ 104,007,000 $ 91,113,000  
Federal net operating loss carryforwards 361,200,000 321,600,000  
State net operating loss carryforwards 205,100,000 186,400,000  
Deferred tax assets operating loss carryforwards will not expired 244,000,000    
Federal research and development tax credit carry-forwards 4,100,000 3,700,000  
State research and development tax credit carry-forwards 4,600,000 4,400,000  
Unrecognized tax benefits 2,156,000 $ 2,020,000 $ 1,791,000
Interest or penalties associated with unrecognized tax benefits $ 0    
Federal      
Income Tax Contingency [Line Items]      
Tax credit carryforward begin to expiration period 2032    
State      
Income Tax Contingency [Line Items]      
Operating loss carryforwards begin to expiration period 2026    
Internal Revenue Code | R&D credit carryforwards      
Income Tax Contingency [Line Items]      
Ownership change percentage 50.00%