<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0206</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2022-06-21</periodOfReport>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0001910851</issuerCik>
        <issuerName>R1 RCM Inc. /DE</issuerName>
        <issuerTradingSymbol>RCM</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001407718</rptOwnerCik>
            <rptOwnerName>New Mountain Capital, L.L.C.</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>1633 BROADWAY, 48TH FLOOR</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10019</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001933650</rptOwnerCik>
            <rptOwnerName>CoyCo 1, L.P.</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O NEW MOUNTAIN CAPITAL, L.L.C.</rptOwnerStreet1>
            <rptOwnerStreet2>1633 BROADWAY, 48TH FLOOR</rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10019</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001933942</rptOwnerCik>
            <rptOwnerName>CoyCo 2, L.P.</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O NEW MOUNTAIN CAPITAL, L.L.C.</rptOwnerStreet1>
            <rptOwnerStreet2>1633 BROADWAY, 48TH FLOOR</rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10019</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001933937</rptOwnerCik>
            <rptOwnerName>CoyCo GP, L.L.C.</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O NEW MOUNTAIN CAPITAL, L.L.C.</rptOwnerStreet1>
            <rptOwnerStreet2>1633 BROADWAY, 48TH FLOOR</rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10019</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001933971</rptOwnerCik>
            <rptOwnerName>New Mountain Partners V (AIV-D), L.P.</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O NEW MOUNTAIN CAPITAL, L.L.C.</rptOwnerStreet1>
            <rptOwnerStreet2>1633 BROADWAY, 48TH FLOOR</rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10019</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001844960</rptOwnerCik>
            <rptOwnerName>New Mountain Investments V, L.L.C.</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O NEW MOUNTAIN CAPITAL, L.L.C.</rptOwnerStreet1>
            <rptOwnerStreet2>1633 BROADWAY, 48TH FLOOR</rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10019</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001777024</rptOwnerCik>
            <rptOwnerName>New Mountain Capital Group, L.P.</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>1633 BROADWAY, 48TH FLOOR</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10019</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001776766</rptOwnerCik>
            <rptOwnerName>NM Holdings GP, L.L.C.</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O NEW MOUNTAIN CAPITAL, L.L.C.</rptOwnerStreet1>
            <rptOwnerStreet2>1633 BROADWAY, 48TH FLOOR</rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10019</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001018327</rptOwnerCik>
            <rptOwnerName>KLINSKY STEVEN B</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O NEW MOUNTAIN CAPITAL, L.L.C.</rptOwnerStreet1>
            <rptOwnerStreet2>1633 BROADWAY, 48TH FLOOR</rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10019</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>124864016</value>
                    <footnoteId id="F1"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>See Notes</value>
                    <footnoteId id="F2"/>
                    <footnoteId id="F3"/>
                    <footnoteId id="F4"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>11065726</value>
                    <footnoteId id="F1"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>See Notes</value>
                    <footnoteId id="F3"/>
                    <footnoteId id="F4"/>
                    <footnoteId id="F5"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">On January 9, 2022, CoyCo 1, L.P. (&quot;CoyCo 1&quot;) and CoyCo 2, L.P. (&quot;CoyCo 2&quot;) entered into a Transaction Agreement and Plan of Merger (the &quot;Transaction Agreement&quot;) with the R1 RCM Inc. (the &quot;Issuer&quot;), its then-parent, Project Roadrunner Merger Sub Inc., a wholly owned subsidiary of the Issuer (&quot;R1 Merger Sub&quot;) and other parties named therein, pursuant to which CoyCo 1 and CoyCo 2 contributed 100% of the equity of a blocker parent of their subsidiaries, which included Cloudmed, to the Issuer in exchange for 135,929,742 shares of common stock of the Issuer (the &quot;Acquisition&quot;).  The Acquisition closed on June 21, 2022 (the &quot;Closing&quot;).</footnote>
        <footnote id="F2">Held directly by CoyCo 1.</footnote>
        <footnote id="F3">CoyCo GP, L.L.C. (&quot;CoyCo GP&quot;) is the general partner of each of CoyCo 1 and CoyCo 2.  New Mountain Partners V (AIV-D), L.P. (&quot;AIV-D&quot;) is the manager of CoyCo GP. New Mountain Investments V, L.L.C. (&quot;Investments V&quot;) has decision-making power over the disposition and voting of securities of portfolio investments of AIV-D.  New Mountain Capital, L.L.C. (&quot;New Mountain Capital&quot;) also has voting power over the securities of portfolio investments of AIV-D. New Mountain Capital Group, L.P. (&quot;New Mountain Capital Group&quot;) is the managing member of New Mountain Capital.  NM Holdings GP, L.L.C. (&quot;NM Holdings GP&quot;) is the general partner of New Mountain Capital Group.  Steven B. Klinsky is the managing member of New Mountain Investments V and managing member of NM Holdings GP.</footnote>
        <footnote id="F4">Because of their relationships, each of Mr. Klinsky, CoyCo GP, AIV-D, New Mountain Investments V, New Mountain Capital, New Mountain Capital Group, and NM Holdings GP may be deemed to beneficially own the Common Shares held by CoyCo 1 and CoyCo 2.  Each of Mr. Klinsky, CoyCo GP, AIV-D, New Mountain Investments V, New Mountain Capital, New Mountain Capital Group, and NM Holdings GP expressly disclaim beneficial ownership over the securities held by CoyCo 1 and CoyCo 2 except to the extent of their pecuniary interest therein.</footnote>
        <footnote id="F5">Held directly by CoyCo 2.</footnote>
    </footnotes>

    <remarks>Subsequent to the Closing, Matthew Holt, Jeremy Delinsky and Kyle Armbrester were appointed to the board of directors of R1 RCM Inc. (the &quot;Issuer&quot;) pursuant to an Investor Rights Agreement between CoyCo 1, CoyCo 2 and the Issuer.  As such, the Reporting Persons may currently be deemed to be &quot;directors by deputization&quot; of the Issuer.</remarks>

    <ownerSignature>
        <signatureName>CoyCo 1, L.P., By: /s/ Adam B. Weinstein, Name: Adam B. Weinstein, Title: Vice President</signatureName>
        <signatureDate>2022-07-01</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>CoyCo 2, L.P.; By its General Partner CoyCo GP, L.L.C., By: /s/ Adam B. Weinstein, Name: Adam B. Weinstein, Title: Vice President</signatureName>
        <signatureDate>2022-07-01</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>CoyCo GP, L.L.C., By: /s/ Adam B. Weinstein, Name: Adam B. Weinstein Title: Vice President</signatureName>
        <signatureDate>2022-07-01</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>New Mountain Partners V (AIV-D), L.P.; By its General Partner New Mountain Investments V, L.L.C., By: /s/ Adam B. Weinstein, Name: Adam B. Weinstein, Title: Authorized Signatory</signatureName>
        <signatureDate>2022-07-01</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>New Mountain Investments V, L.L.C., By: /s/ Adam B. Weinstein, Name: Adam B. Weinstein, Title: Authorized Signatory</signatureName>
        <signatureDate>2022-07-01</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>New Mountain Capital Group, L.P.; By its General Partner NM Holdings GP, L.L.C., By: /s/ Adam B. Weinstein, Name: Adam B. Weinstein, Title: Authorized Signatory</signatureName>
        <signatureDate>2022-07-01</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>NM Holdings GP, L.L.C., By: /s/ Adam B. Weinstein, Name: Adam B. Weinstein, Title: Authorized Signatory</signatureName>
        <signatureDate>2022-07-01</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>Steven B. Klinsky, /s/ Steven B. Klinsky</signatureName>
        <signatureDate>2022-07-01</signatureDate>
    </ownerSignature>
</ownershipDocument>
