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Consolidated Statements of Changes in Convertible Preferred Stock and Stockholders’ Deficit - USD ($)
$ in Thousands
Total
Conversion of convertible preferred stock into common stock and pre-funded warrants in connection with the reverse merger
Series A-1 Convertible Preferred Stock
Series A-2 Convertible Preferred Stock
Series B Convertible Preferred Stock
Class A Common Stock
Class B Common Stock
Preferred Stock
Common Stock
Common Stock
Conversion of convertible preferred stock into common stock and pre-funded warrants in connection with the reverse merger
Common Stock
Conversion of Class A common stock into common stock and related change in par value
Common Stock
Class A Common Stock
Common Stock
Class A Common Stock
Conversion of Class A common stock into common stock and related change in par value
Common Stock
Class B Common Stock
Additional Paid- In Capital
Additional Paid- In Capital
Conversion of convertible preferred stock into common stock and pre-funded warrants in connection with the reverse merger
Accumulated Deficit
Beginning balance (in shares) at Dec. 31, 2021     18,604,653 13,291,208 47,131,133                        
Beginning balance at Dec. 31, 2021     $ 34,414 $ 28,675 $ 114,818                        
Increase (Decrease) in Temporary Equity [Roll Forward]                                  
Series B convertible preferred stock, net of offering costs (in shares)         27,274,586                        
Series B convertible preferred stock, net of $91 offering costs         $ 66,459                        
Ending balance at Dec. 31, 2022 $ 244,366   $ 34,414 $ 28,675 $ 181,277                        
Ending balance (in shares) at Dec. 31, 2022     18,604,653 13,291,208 74,405,719                        
Beginning balance (in shares) at Dec. 31, 2021               0                  
Beginning balance (in shares) at Dec. 31, 2021                 0     419,783   0      
Beginning balance at Dec. 31, 2021 (91,875)             $ 0 $ 0     $ 0   $ 0 $ 3,773   $ (95,648)
Increase (Decrease) in Stockholders' Equity [Roll Forward]                                  
Stock-based compensation expense 1,252                                
Class A common stock issued upon exercise of stock options (in shares)                       8,551          
Class A common stock issued upon exercise of stock options 73                                
Net loss (55,189)         $ (55,189) $ 0                    
Ending balance at Dec. 31, 2022 $ (145,739)             $ 0 $ 0     $ 0   $ 0 5,098   (150,837)
Ending balance (in shares) at Dec. 31, 2022 0         428,334 0   0     428,334   0      
Ending balance (in shares) at Dec. 31, 2022 0             0                  
Ending balance at Mar. 31, 2023     $ 34,414 $ 28,675 $ 181,277                        
Ending balance (in shares) at Mar. 31, 2023     18,604,653 13,291,208 74,405,719                        
Increase (Decrease) in Stockholders' Equity [Roll Forward]                                  
Stock-based compensation expense $ 293                           293    
Class A common stock issued upon exercise of stock options (in shares)                       13,532          
Class A common stock issued upon exercise of stock options 112                           112    
Net loss (12,263)                               (12,263)
Ending balance at Mar. 31, 2023 (157,597)             $ 0 $ 0     $ 0   $ 0 5,503   (163,100)
Ending balance (in shares) at Mar. 31, 2023                 0     441,866   0      
Ending balance (in shares) at Mar. 31, 2023               0                  
Beginning balance (in shares) at Dec. 31, 2022     18,604,653 13,291,208 74,405,719                        
Beginning balance at Dec. 31, 2022 $ 244,366   $ 34,414 $ 28,675 $ 181,277                        
Ending balance at Sep. 30, 2023     $ 34,414 $ 28,675 $ 181,277                        
Ending balance (in shares) at Sep. 30, 2023     18,604,653 13,291,208 74,405,719                        
Beginning balance (in shares) at Dec. 31, 2022 0             0                  
Beginning balance (in shares) at Dec. 31, 2022 0         428,334 0   0     428,334   0      
Beginning balance at Dec. 31, 2022 $ (145,739)             $ 0 $ 0     $ 0   $ 0 5,098   (150,837)
Increase (Decrease) in Stockholders' Equity [Roll Forward]                                  
Net loss (38,700)         $ (38,700) $ 0                    
Ending balance at Sep. 30, 2023 (183,209)             $ 0 $ 0     $ 0   $ 0 6,328   (189,537)
Ending balance (in shares) at Sep. 30, 2023                 0     448,644   0      
Ending balance (in shares) at Sep. 30, 2023               0                  
Beginning balance (in shares) at Dec. 31, 2022     18,604,653 13,291,208 74,405,719                        
Beginning balance at Dec. 31, 2022 $ 244,366   $ 34,414 $ 28,675 $ 181,277                        
Beginning balance (in shares) at Dec. 31, 2022 0             0                  
Beginning balance (in shares) at Dec. 31, 2022 0         428,334 0   0     428,334   0      
Beginning balance at Dec. 31, 2022 $ (145,739)             $ 0 $ 0     $ 0   $ 0 5,098   (150,837)
Increase (Decrease) in Stockholders' Equity [Roll Forward]                                  
Net loss           $ (49,971) $ 0                    
Ending balance (in shares) at Dec. 18, 2023           12,823,665                      
Beginning balance (in shares) at Dec. 31, 2022     18,604,653 13,291,208 74,405,719                        
Beginning balance at Dec. 31, 2022 244,366   $ 34,414 $ 28,675 $ 181,277                        
Increase (Decrease) in Temporary Equity [Roll Forward]                                  
Additional convertible preferred stock issued in conjunction with anti-dilution adjustment (in shares)     1,890,302 1,350,436 10,264,533                        
Conversion of convertible preferred stock into common stock and pre-funded warrants in connection with the reverse merger (in shares)     (20,494,955) (14,641,644) (84,670,252)                        
Conversion of convertible preferred stock into common stock and pre-funded warrants in connection with the reverse merger     $ (34,414) $ (28,675) $ (181,277)                        
Ending balance at Dec. 31, 2023 $ 0   $ 0 $ 0 $ 0                        
Ending balance (in shares) at Dec. 31, 2023     0 0 0                        
Beginning balance (in shares) at Dec. 31, 2022 0             0                  
Beginning balance (in shares) at Dec. 31, 2022 0         428,334 0   0     428,334   0      
Beginning balance at Dec. 31, 2022 $ (145,739)             $ 0 $ 0     $ 0   $ 0 5,098   (150,837)
Increase (Decrease) in Stockholders' Equity [Roll Forward]                                  
Stock-based compensation expense $ 1,418                           1,418    
Class A common stock issued upon exercise of stock options (in shares) 20,348                     20,348          
Class A common stock issued upon exercise of stock options $ 168                           168    
Conversion of convertible preferred stock into common stock and pre-funded warrants in connection with the reverse merger (in shares)                   7,231,747 (3,240,888)   3,240,888        
Conversion of convertible preferred stock into common stock and pre-funded warrants in connection with the reverse merger   $ 244,366                           $ 244,366  
Issuance of Class A common stock and pre-funded warrants in the pre-closing financing, net of $6,946 offering costs (in shares)                       2,792,206          
Issuance of Class A common stock and pre-funded warrants in the pre-closing financing, net of $6,946 offering costs 88,056                           88,056    
Transactions costs associated with the reverse merger (4,140)                           (4,140)    
Issuance of common stock and pre-funded warrants to former stockholders of Neoleukin Therapeutics, Inc. in connection with the reverse merger (in shares)                 2,351,030                
Issuance of common stock and pre-funded warrants to former stockholders of Neoleukin Therapeutics, Inc. in connection with the reverse merger 38,212                           38,212    
Net loss (36,317)                               (36,317)
Ending balance at Dec. 31, 2023 $ 186,024             $ 0 $ 0     $ 0   $ 0 373,178   (187,154)
Ending balance (in shares) at Dec. 31, 2023 12,823,665         0 0   12,823,665     0   0      
Ending balance (in shares) at Dec. 31, 2023 0             0                  
Beginning balance (in shares) at Mar. 31, 2023     18,604,653 13,291,208 74,405,719                        
Beginning balance at Mar. 31, 2023     $ 34,414 $ 28,675 $ 181,277                        
Ending balance at Jun. 30, 2023     $ 34,414 $ 28,675 $ 181,277                        
Ending balance (in shares) at Jun. 30, 2023     18,604,653 13,291,208 74,405,719                        
Beginning balance (in shares) at Mar. 31, 2023               0                  
Beginning balance (in shares) at Mar. 31, 2023                 0     441,866   0      
Beginning balance at Mar. 31, 2023 $ (157,597)             $ 0 $ 0     $ 0   $ 0 5,503   (163,100)
Increase (Decrease) in Stockholders' Equity [Roll Forward]                                  
Stock-based compensation expense 384                           384    
Class A common stock issued upon exercise of stock options (in shares)                       2,751          
Class A common stock issued upon exercise of stock options 20                           20    
Net loss (11,860)                               (11,860)
Ending balance at Jun. 30, 2023 (169,053)             $ 0 $ 0     $ 0   $ 0 5,907   (174,960)
Ending balance (in shares) at Jun. 30, 2023                 0     444,617   0      
Ending balance (in shares) at Jun. 30, 2023               0                  
Ending balance at Sep. 30, 2023     $ 34,414 $ 28,675 $ 181,277                        
Ending balance (in shares) at Sep. 30, 2023     18,604,653 13,291,208 74,405,719                        
Increase (Decrease) in Stockholders' Equity [Roll Forward]                                  
Stock-based compensation expense 386                           386    
Class A common stock issued upon exercise of stock options (in shares)                       4,027          
Class A common stock issued upon exercise of stock options 35                           35    
Net loss (14,577)                               (14,577)
Ending balance at Sep. 30, 2023 (183,209)             $ 0 $ 0     $ 0   $ 0 6,328   (189,537)
Ending balance (in shares) at Sep. 30, 2023                 0     448,644   0      
Ending balance (in shares) at Sep. 30, 2023               0                  
Ending balance at Dec. 31, 2023 0   $ 0 $ 0 $ 0                        
Ending balance (in shares) at Dec. 31, 2023     0 0 0                        
Beginning balance (in shares) at Dec. 18, 2023           12,823,665                      
Increase (Decrease) in Stockholders' Equity [Roll Forward]                                  
Net loss 13,654                                
Ending balance at Dec. 31, 2023 $ 186,024             $ 0 $ 0     $ 0   $ 0 373,178   (187,154)
Ending balance (in shares) at Dec. 31, 2023 12,823,665         0 0   12,823,665     0   0      
Ending balance (in shares) at Dec. 31, 2023 0             0                  
Ending balance at Mar. 31, 2024     $ 0 $ 0 $ 0                        
Ending balance (in shares) at Mar. 31, 2024     0 0 0                        
Increase (Decrease) in Stockholders' Equity [Roll Forward]                                  
Stock-based compensation expense $ 1,045                           1,045    
Class A common stock issued upon exercise of stock options (in shares)                 37,330                
Class A common stock issued upon exercise of stock options 629                           629    
Net loss (16,921)                               (16,921)
Ending balance at Mar. 31, 2024 170,777             $ 0 $ 0     $ 0   $ 0 374,852   (204,075)
Ending balance (in shares) at Mar. 31, 2024                 12,860,995     0   0      
Ending balance (in shares) at Mar. 31, 2024               0                  
Beginning balance (in shares) at Dec. 31, 2023     0 0 0                        
Beginning balance at Dec. 31, 2023 $ 0   $ 0 $ 0 $ 0                        
Ending balance at Sep. 30, 2024     $ 0 $ 0 $ 0                        
Ending balance (in shares) at Sep. 30, 2024     0 0 0                        
Beginning balance (in shares) at Dec. 31, 2023 0             0                  
Beginning balance (in shares) at Dec. 31, 2023 12,823,665         0 0   12,823,665     0   0      
Beginning balance at Dec. 31, 2023 $ 186,024             $ 0 $ 0     $ 0   $ 0 373,178   (187,154)
Increase (Decrease) in Stockholders' Equity [Roll Forward]                                  
Class A common stock issued upon exercise of stock options (in shares) 83,795                                
Net loss $ (55,630)                                
Ending balance at Sep. 30, 2024 $ 137,414             $ 0 $ 0     $ 0   $ 0 380,198   (242,784)
Ending balance (in shares) at Sep. 30, 2024 13,010,867               13,010,867     0   0      
Ending balance (in shares) at Sep. 30, 2024 0             0                  
Beginning balance (in shares) at Mar. 31, 2024     0 0 0                        
Beginning balance at Mar. 31, 2024     $ 0 $ 0 $ 0                        
Ending balance at Jun. 30, 2024     $ 0 $ 0 $ 0                        
Ending balance (in shares) at Jun. 30, 2024     0 0 0                        
Beginning balance (in shares) at Mar. 31, 2024               0                  
Beginning balance (in shares) at Mar. 31, 2024                 12,860,995     0   0      
Beginning balance at Mar. 31, 2024 $ 170,777             $ 0 $ 0     $ 0   $ 0 374,852   (204,075)
Increase (Decrease) in Stockholders' Equity [Roll Forward]                                  
Stock-based compensation expense 2,314                           2,314    
Class A common stock issued upon exercise of stock options (in shares)                 24,806                
Class A common stock issued upon exercise of stock options 415                           415    
Net loss (18,492)                               (18,492)
Ending balance at Jun. 30, 2024 155,014             $ 0 $ 0     $ 0   $ 0 377,581   (222,567)
Ending balance (in shares) at Jun. 30, 2024                 12,989,208     0   0      
Ending balance (in shares) at Jun. 30, 2024               0                  
Ending balance at Sep. 30, 2024     $ 0 $ 0 $ 0                        
Ending balance (in shares) at Sep. 30, 2024     0 0 0                        
Increase (Decrease) in Stockholders' Equity [Roll Forward]                                  
Stock-based compensation expense 2,474                           2,474    
Class A common stock issued upon exercise of stock options (in shares)                 21,659                
Class A common stock issued upon exercise of stock options 143                           143    
Net loss (20,217)                               (20,217)
Ending balance at Sep. 30, 2024 $ 137,414             $ 0 $ 0     $ 0   $ 0 $ 380,198   $ (242,784)
Ending balance (in shares) at Sep. 30, 2024 13,010,867               13,010,867     0   0      
Ending balance (in shares) at Sep. 30, 2024 0             0