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Equity (Tables)
9 Months Ended
Sep. 30, 2023
Equity [Abstract]  
Summary of Stock-based Compensation Expense
Stock-based compensation expense is classified in the condensed statements of operations and comprehensive income (loss) as follows:
(in thousands)Three Months Ended
September 30,
Nine Months Ended
September 30,
2023202220232022
Research and development expenses$— $973 $252 $3,288 
General and administrative expenses172 1,058 1,442 3,501 
Total stock-based compensation expense$172 $2,031 $1,694 $6,789 
Schedule of Weighted Average Assumptions
The fair values of stock options granted are estimated using the Black-Scholes option pricing model with the following weighted average assumptions:
 Three Months Ended
September 30,
Nine Months Ended
September 30,
 2023202220232022
Expected volatility— 84.18 %86.77 %83.80 %
Expected dividends— %%%
Expected terms (years)— 6.085.606.04
Risk free rate— 2.83 %3.67 %2.63 %
Schedule of Stock Option Activity
A summary of the Company’s stock option activity and related information for the nine months ended September 30, 2023 is as follows:
 Number of SharesWeighted Average Exercise PriceWeighted Average Remaining Contractual Life
 (in Years)
Aggregate Intrinsic Value
(in Thousands)
Outstanding at December 31, 20221,702,833 $24.47 8.32$— 
Options granted52,100 $3.52 
Options exercised— $— 
Options cancelled/forfeited(859,867)$27.06 
Outstanding at September 30, 2023895,066 $19.70 4.03$
Exercisable as of September 30, 2023738,616 $21.90 3.04$— 
Summary of RSU Activity
A summary of the Company’s RSU activity and related information for the nine months ended September 30, 2023 is as follows:
 Number of SharesWeighted Average Grant Date Fair Value
Non-vested at December 31, 202275,700 $21.09 
Restricted stock units granted— $— 
Restricted stock units vested(37,000)$21.95 
Restricted stock units forfeited(32,950)$20.59 
Non-vested at September 30, 20235,750 $18.45