Leases - Additional Information (Details) $ in Thousands	1 Months Ended	12 Months Ended
	Dec. 31, 2022 USD ($) ft²	Dec. 31, 2022 USD ($) ft² option	Dec. 31, 2021 USD ($)	Jan. 31, 2020 USD ($)
Lessee, Lease, Description [Line Items]
Security deposit	$ 900	$ 900
Tenant improvement allowance		9,500
Base lease payments	500
Increase in lease liability		(1,165)	$ (687)
Loss on disposal of property and equipment		118	0
Operating lease right-of-use asset	9,715	9,715	10,766
Finance lease right-of-use asset	$ 500	$ 500	$ 200
Finance Lease, Right-of-Use Asset, Statement of Financial Position [Extensible Enumeration]	Property and equipment, net	Property and equipment, net	Property and equipment, net
Standby Letters of Credit
Lessee, Lease, Description [Line Items]
Security deposit				$ 500
Washington | Office space, principal executive offices and laboratory
Lessee, Lease, Description [Line Items]
Lease agreement, square feet of office space | ft²	33,300	33,300
Number of options to extend lease | option		2
Lease agreement extended period		5 years
Washington | Office space, former principal executive offices and laboratory
Lessee, Lease, Description [Line Items]
Lease agreement, square feet of office space | ft²	6,272	6,272
Washington | Office space, additional offices and laboratory
Lessee, Lease, Description [Line Items]
Renewal term	28 months	28 months
Increase in right-of-use-asset		$ 1,600
Increase in lease liability		$ 1,600