Income taxes - Additional Information (Details) - USD ($) $ in Thousands		12 Months Ended
	Jul. 31, 2020	Dec. 31, 2021	Dec. 31, 2020
Income Taxes Disclosure [Line Items]
Gain on sale of Aquinox Canada		$ 0	$ 7,826
Net operating losses carried forward for tax purposes		108,200	58,100
Operating loss carryforwards subject to expiration		1,700
Operating loss carryforwards not subject to expiration		106,500
Increase (decrease) in valuation allowance		12,900	(42,900)
Research Tax Credit Carryforward
Income Taxes Disclosure [Line Items]
Tax credits for research and development		$ 2,400	$ 1,000
Acqinox Canada
Income Taxes Disclosure [Line Items]
Gain on sale of Aquinox Canada	$ 7,800
Tax attributes no longer reflected in deferred tax assets and valuation allowance	$ 51,700