Leases - Additional Information (Details) $ in Thousands	1 Months Ended	12 Months Ended
	Jun. 30, 2020 USD ($) ft²	Dec. 31, 2021 USD ($) ft² option	Dec. 31, 2020 USD ($)	Jan. 31, 2020 USD ($)
Lessee, Lease, Description [Line Items]
Tenant improvement allowance		$ 9,500
Increase in right-of-use-asset		0	$ 169
Increase in lease liability		(687)	598
Termination fees for lease termination	$ 500
Loss on termination of lease	300
Loss on disposal of property and equipment	$ 200	0	180
Operating lease right-of-use asset		10,766	10,154
Finance lease right-of-use asset		$ 200	$ 300
Finance Lease, Right-of-Use Asset, Statement of Financial Position [Extensible Enumeration]		Property and equipment, net	Property and equipment, net
Standby Letters of Credit
Lessee, Lease, Description [Line Items]
Security deposit				$ 500
Washington
Lessee, Lease, Description [Line Items]
Number of options to extend lease | option		2
Lease agreement extended period		5 years
Washington | Office space, principal executive offices and laboratory
Lessee, Lease, Description [Line Items]
Lease agreement, square feet of office space | ft²		33,300
Number of options to extend lease | option		2
Lease agreement extended period		5 years
Washington | Office space, former principal executive offices and laboratory
Lessee, Lease, Description [Line Items]
Lease agreement, square feet of office space | ft²		6,272
Washington | Office space, additional offices and laboratory
Lessee, Lease, Description [Line Items]
Renewal term		28 months
Increase in right-of-use-asset		$ 1,600
Increase in lease liability		$ 1,600
Canada
Lessee, Lease, Description [Line Items]
Lease agreement, square feet of office space | ft²	10,946