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Net loss per common stock
 12 Months Ended
Dec. 31, 2021
Earnings Per Share [Abstract]  
Net loss per common stock Net loss per common stock
The Company excluded the following potentially dilutive shares from diluted net loss per share as the effect would have been anti-dilutive for all periods presented:
December 31,
20212020
Outstanding stock options8,963,945 6,848,289 
Restricted stock units132,000 186,500 
Shares issuable under 2020 ESPP53,446 22,521 
9,149,391 7,057,310