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Pay vs Performance Disclosure - USD ($)
 12 Months Ended
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
Pay vs Performance Disclosure      
Pay vs Performance Disclosure, Table
Year
Summary Compensation Table Total for Dr. McMinn1
Compensation Actually Paid to Dr. McMinn2
Summary Compensation Table Total for Ms. Cochener1
Compensation Actually Paid to Ms. Cochener2
Summary Compensation Table Total for Dr. Drachman1
Compensation Actually Paid to Dr. Drachman2
Average Summary Compensation Table Total for Non-Principal Executive Officer (“PEO”) NEOs3
Average Compensation Actually Paid to Non-PEO NEOs4
Value of Initial Fixed $100 Investment Based On Total Shareholder Return (“TSR”)5
Net Income (Loss)6 (in thousands)
20231,080,629 1,041,892 1,827,432 1,902,501 549,983 477,211 1,242,197 1,252,222 7.00 (36,317)
2022––––––––902,179 (3,599,400)1,027,439 (119,619)3.61 (60,692)
2021––––––––2,650,131 (9,588,163)3,457,798 103,358 34.18 (57,557)
    
Named Executive Officers, Footnote The dollar amounts reported are the amounts of total compensation reported in our Summary Compensation Table. The dollar amounts reported represent the average of the amounts reported for the Company’s NEOs as a group (excluding the PEO(s)) in the “Total” column of the Summary Compensation Table in each applicable year. The names of each of the NEOs (excluding the PEO(s)) included for purposes of calculating the average amounts in each applicable year are as follows: (i) for 2023, Ms. Mikail, Dr. Cobb, and Mr. Smith; (ii) for 2022, Ms. Cochener and Dr. Patel; and (iii) for 2021, Robert Ho, our former Chief Financial Officer, and Dr. Patel.    
Peer Group Issuers, Footnote Cumulative TSR is calculated by dividing the sum of the cumulative amount of dividends, if any, for the measurement period, assuming dividend reinvestment, and the difference between the Company’s stock price at the end and the beginning of the measurement period by the Company’s stock price at the beginning of the measurement period. The beginning of the measurement period for each year in the table is December 31, 2020.    
Adjustment To PEO Compensation, Footnote The dollar amounts reported represent the amount of “compensation actually paid” to each of the PEOs during the applicable year, as computed in accordance with SEC rules. The dollar amounts do not reflect the actual amount of compensation earned by or paid to the PEOs during the applicable year. In accordance with SEC rules, these amounts reflect “Total Compensation” as set forth in the Summary Compensation Table for each year, adjusted as shown below. Equity values are calculated in accordance with FASB ASC Topic 718, and the valuation assumptions used to calculate fair values did not materially differ from those disclosed at the time of grant.
Compensation Actually Paid to PEO
2023
(Dr. McMinn)
2023
(Ms. Cochener)
2023
(Dr. Drachman)
Summary Compensation Table Total1,080,629 1,827,432 549,983 
Less, value of “Option Awards” reported in Summary Compensation Table
(404,087)— — 
Plus, year-end fair value of outstanding and unvested equity awards granted in the year399,010 — — 
Plus (less), year over year change in fair value of outstanding and unvested equity awards granted in prior years(22,191)— — 
Plus (less), change in fair value from prior year end to the vesting date of equity awards granted in prior years that vested in the year
(11,469)75,069 69,814 
Less, prior year-end fair value for any equity awards forfeited in the year— — (142,586)
Compensation Actually Paid to PEO1,041,892 1,902,501 477,211 
    
Non-PEO NEO Average Total Compensation Amount $ 1,242,197 $ 1,027,439 $ 3,457,798
Non-PEO NEO Average Compensation Actually Paid Amount $ 1,252,222 (119,619) 103,358
Adjustment to Non-PEO NEO Compensation Footnote The dollar amounts reported represent the average amount of “compensation actually paid” to the NEOs as a group (excluding the PEO(s)), as computed in accordance with SEC rules. The dollar amounts do not reflect the actual average amount of compensation earned by or paid to the NEOs as a group (excluding the PEO(s)) during the applicable year. In accordance with the SEC rules, these amounts reflect “Total” as set forth in the Summary Compensation Table for each year, adjusted as shown below. Equity values are calculated in accordance with FASB ASC Topic 718, and the valuation assumptions used to calculate fair values did not materially differ from those disclosed at the time of the grant.
Average Compensation Actually Paid to Non-PEO NEOs2023
Average Summary Compensation Table Total1,242,197 
Less, average value of “Option Awards” and “Stock Awards” reported in Summary Compensation Table
(271,571)
Plus, average year-end fair value of outstanding and unvested equity awards granted in the year283,155 
Plus, average fair value as of vesting date of equity awards granted and vested in the year— 
Plus (less), average year over year change in fair value of outstanding and unvested equity awards granted in prior years(10,632)
Plus (less), average change in fair value from the prior year end to the vesting date of equity awards granted in prior years that vested in the year
9,073 
Less, prior year-end fair value for any equity awards forfeited in the year— 
Average Compensation Actually Paid to Non-PEO NEOs
1,252,222 
    
Compensation Actually Paid vs. Total Shareholder Return
The following chart sets forth the relationship between Compensation Actually Paid to our PEO(s), the average of Compensation Actually Paid to our non-PEO NEOs, and the Company’s TSR over the fiscal three year period from 2021 through 2023:

Relationship Between NEO comp actually paid and company TSR.jpg
    
Compensation Actually Paid vs. Net Income
The following chart sets forth the relationship between Compensation Actually Paid to our PEO(s), the average of Compensation Actually Paid to our Non-PEO NEOs, and the Company’s Net Income (Loss) over the two fiscal year period from 2021 through 2023:
Relationship Between NEO Compensation Actually Paid and Net loss.jpg
    
Total Shareholder Return Amount $ 7.00 3.61 34.18
Net Income (Loss) $ (36,317,000) (60,692,000) (57,557,000)
Additional 402(v) Disclosure The dollar amounts reported represent the amount of net income (loss) reflected in the Company’s audited financial statements for the applicable year.    
Dr. McMinn [Member]      
Pay vs Performance Disclosure      
PEO Total Compensation Amount $ 1,080,629    
PEO Actually Paid Compensation Amount 1,041,892    
Ms. Cochener [Member]      
Pay vs Performance Disclosure      
PEO Total Compensation Amount 1,827,432    
PEO Actually Paid Compensation Amount 1,902,501    
Dr. Drachman [Member]      
Pay vs Performance Disclosure      
PEO Total Compensation Amount 549,983 902,179 2,650,131
PEO Actually Paid Compensation Amount 477,211 $ (3,599,400) $ (9,588,163)
PEO | Dr. McMinn [Member] | Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount (404,087)    
PEO | Dr. McMinn [Member] | Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount 399,010    
PEO | Dr. McMinn [Member] | Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount (22,191)    
PEO | Dr. McMinn [Member] | Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount (11,469)    
PEO | Dr. McMinn [Member] | Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount 0    
PEO | Ms. Cochener [Member] | Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount 0    
PEO | Ms. Cochener [Member] | Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount 0    
PEO | Ms. Cochener [Member] | Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount 0    
PEO | Ms. Cochener [Member] | Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount 75,069    
PEO | Ms. Cochener [Member] | Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount 0    
PEO | Dr. Drachman [Member] | Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount 0    
PEO | Dr. Drachman [Member] | Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount 0    
PEO | Dr. Drachman [Member] | Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount 0    
PEO | Dr. Drachman [Member] | Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount 69,814    
PEO | Dr. Drachman [Member] | Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount (142,586)    
Non-PEO NEO | Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount (271,571)    
Non-PEO NEO | Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount 283,155    
Non-PEO NEO | Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount (10,632)    
Non-PEO NEO | Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount 0    
Non-PEO NEO | Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount 9,073    
Non-PEO NEO | Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year      
Pay vs Performance Disclosure      
Adjustment to Compensation, Amount $ 0