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Summary of significant accounting policies - Additional Information (Details)
3 Months Ended 6 Months Ended 12 Months Ended
Jun. 30, 2023
USD ($)
shares
Jun. 30, 2022
USD ($)
shares
Jun. 30, 2023
USD ($)
shares
Jun. 30, 2022
USD ($)
shares
Dec. 31, 2022
USD ($)
segment
shares
Dec. 31, 2021
shares
Lessee, Lease, Description [Line Items]            
Security deposit $ 500,000   $ 500,000   $ 900,000  
Outstanding pre-funded warrants (in shares) | shares         2,532,602 2,532,602
Number of operating segments | segment         1  
Fair value, investments, unrealized loss 31,100,000   31,100,000   $ 40,700,000  
Impairment of property and equipment 0 $ 0 3,418,000 $ 0    
Allowance for credit loss $ 0   $ 0      
Expected dividends 0.00% 0.00% 0.00% 0.00% 0.00% 0.00%
Prefunded Warrants            
Lessee, Lease, Description [Line Items]            
Outstanding pre-funded warrants (in shares) | shares 2,296,602 2,532,602 2,296,602 2,532,602    
Minimum            
Lessee, Lease, Description [Line Items]            
Property and equipment, useful life 3 years   3 years   3 years  
Maximum            
Lessee, Lease, Description [Line Items]            
Property and equipment, useful life 7 years   7 years   7 years  
Office space | Maximum            
Lessee, Lease, Description [Line Items]            
Lease term 12 months   12 months   12 months