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Stockholders' equity (Tables)
12 Months Ended
Dec. 31, 2019
Federal Home Loan Banks [Abstract]  
Schedule of Stock Option Transactions and Number of Stock Options Outstanding
Stock option transactions and the number of stock options outstanding are summarized below:
 
   
NUMBER OF

SHARES
   
WEIGHTED
AVERAGE
EXERCISE PRICE
   
WEIGHTED
AVERAGE
REMAINING
CONTRACTUAL
LIFE

(IN YEARS)
   
AGGREGATE
INTRINSIC
 
VALUE
(
IN
 
THOUSANDS)
 
Outstanding at December 31, 2018
   2,897,294   $9.04    7.96   $—   
Options granted
   4,016,500    2.91           
Options exercised
   (326,094)    4.77           
Options forfeited
   (747,162)    8.71           
  
 
 
   
 
 
   
 
 
   
 
 
 
Outstanding at December 31, 2019
   5,840,538   $5.11    7.72   $45,037 
  
 
 
   
 
 
   
 
 
   
 
 
 
Exercisable as of December 31, 2019
   1,805,043   $9.85    3.36   $7,264 
Schedule of Weighted Average Assumptions
The fair value of stock options granted is estimated using the Black-Scholes option pricing model with the following weighted average assumptions:
 
   
YEARS ENDED DECEMBER 31,
 
   
2019
  
2018
  
2017
 
Expected volatility
   90%   80%   84% 
Expected dividends
   0%   0%   0% 
Expected terms (years)
   6.07   6.00   6.00 
Risk free rate
   1.43%   2.80%   1.90% 
Weighted average grant-date fair value of stock options
  $2.17  $6.24  $11.85