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Stockholders' equity - Schedule of Weighted Average Assumptions (Detail) - $ / shares
3 Months Ended 9 Months Ended
Sep. 30, 2019
Sep. 30, 2018
Sep. 30, 2019
Sep. 30, 2018
Disclosure of Compensation Related Costs, Share-based Payments [Abstract]        
Expected volatility 90.00% 83.00% 90.00% 80.00%
Expected dividends 0.00% 0.00% 0.00% 0.00%
Expected terms (years) 6 years 6 years 6 years 6 years
Risk free rate 1.44% 2.86% 1.44% 2.80%
Weighted average grant-date fair value of stock options $ 2.63 $ 2.20 $ 2.63 $ 6.25