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Stockholders' equity - Schedule of Weighted Average Assumptions (Detail) - $ / shares
3 Months Ended 6 Months Ended
Jun. 30, 2018
Jun. 30, 2018
Disclosure of Compensation Related Costs, Share-based Payments [Abstract]    
Expected volatility 86.00% 77.00%
Expected dividends 0.00% 0.00%
Expected terms (years) 6 years 6 years
Risk free rate 2.82% 2.74%
Weighted average grant-date fair value of stock options $ 9.60 $ 10.83