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Accounts payable and other liabilities (Tables)
12 Months Ended
Dec. 31, 2017
Payables and Accruals [Abstract]  
Schedule of Accounts Payable and Other Liabilities
(in thousands)    DECEMBER 31,
2017
     DECEMBER 31,
2016
 

Trade accounts payable

   $ 6,016      $ 6,860  

Accrued clinical/preclinical expenses

     2,667        1,381  

Accrued compensation and vacation

     1,553        1,024  

Other liabilities

     720        254  
  

 

 

    

 

 

 
   $ 10,956      $ 9,519