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Net loss per common stock - Schedule of Antidilutive Securities Excluded from Computation of Basic and Diluted Net Loss Per Common Stock (Detail) - shares
3 Months Ended
Mar. 31, 2017
Mar. 31, 2016
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]    
Antidilutive securities excluded from the computation of basic and diluted net loss per share 2,015,389 1,266,936
Outstanding Stock Options [Member]    
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]    
Antidilutive securities excluded from the computation of basic and diluted net loss per share 2,015,389 1,255,573
Warrants to Purchase Common Stock [Member]    
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]    
Antidilutive securities excluded from the computation of basic and diluted net loss per share   11,363