Accounts Payable and Other Liabilities - Schedule of Accounts Payable and Other Liabilities (Detail) - USD ($) $ in Thousands	Dec. 31, 2015	Dec. 31, 2014
Payables and Accruals [Abstract]
Trade accounts payable	$ 2,205	$ 734
Accrued clinical trial fees	1,666	3,752
Accrued compensation and vacation	692	382
Accrued professional fees	128	247
Other liabilities	101	88
Accounts payable and other liabilities	$ 4,792	$ 5,203