Condensed Consolidated Statements of Cash Flows - USD ($) $ in Thousands	6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021
Cash flows from operating activities:
Net loss	$ (137,244)	$ (112,112)
Items not involving cash:
Depreciation of property and equipment	3,683	1,945
Amortization of intangible assets	320	2,180
Stock-based compensation (recovery) expense	(5,282)	6,400
Amortization of operating lease right-of-use assets	3,500	1,255
Deferred income tax expense (recovery)	470	(405)
Change in fair value of contingent consideration liability	(250)	31
Change in fair value of investments in equity instruments	0	(167)
Unrealized foreign exchange (gain) loss	(434)	921
Changes in non-cash operating working capital:
Accounts receivable	11,476	6,133
Prepaid expenses and other current assets	(127)	(10,000)
Accounts payable and accrued liabilities	13,550	10,339
Operating lease liabilities	102	2,325
Net cash used in operating activities	(110,236)	(91,155)
Cash flows from financing activities:
Proceeds from public offering, net of issuance costs (notes 8a, 8d)	107,534	0
Issuance of common shares on exercise of stock options (note 8f)	19	2,084
Issuance of common shares through employee stock purchase plan	863	829
Deferred financing fees	(76)	(128)
Finance lease payments	(9)	(8)
Net cash provided by financing activities	108,331	2,777
Cash flows from investing activities:
Net redemptions of short-term investments	7,094	106,573
Acquisition of property and equipment	(6,821)	(2,447)
Acquisition of intangible assets	(1,629)	(40)
Net cash (used in) provided by investing activities	(1,356)	104,086
Effect of exchange rate changes on cash and cash equivalents	43	(585)
Net change in cash and cash equivalents	(3,218)	15,123
Cash and cash equivalents, beginning of period	201,867	242,036
Cash and cash equivalents, end of period	198,649	257,159
Supplemental disclosure of non-cash investing and financing items:
Leased assets obtained in exchange for operating lease liabilities	72	21,279
Acquisition of property and equipment in accounts payable and accrued liabilities	$ 1,003	$ 1,281