Condensed Consolidated Statements of Loss and Comprehensive Loss - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021	Jun. 30, 2022	Jun. 30, 2021
Revenue
Research and development collaborations (note 9)	$ 5,442	$ 1,771	$ 7,358	$ 2,415
Operating expenses:
Research and development	56,022	50,711	118,532	94,994
General and administrative	15,243	19,945	27,335	21,241
Total operating expenses	71,265	70,656	145,867	116,235
Loss from operations	(65,823)	(68,885)	(138,509)	(113,820)
Other income:
Interest income	436	588	738	1,329
Other income, net (note 10)	759	341	444	470
Total other income, net	1,195	929	1,182	1,799
Loss before income taxes	(64,628)	(67,956)	(137,327)	(112,021)
Income tax recovery (expense)	9	434	83	(91)
Net loss and comprehensive loss	(64,619)	(67,522)	(137,244)	(112,112)
Net loss and comprehensive loss	$ (64,619)	$ (67,522)	$ (137,244)	$ (112,112)
Net loss per common share (note 4):
Basic (in dollars per share)	$ (0.97)	$ (1.31)	$ (2.15)	$ (2.18)
Diluted (in dollars per share)	$ (0.97)	$ (1.31)	$ (2.15)	$ (2.42)
Weighted-average common shares outstanding (note 4):
Basic (in shares)	66,353,279	51,422,066	63,874,097	51,395,015
Diluted (in shares)	66,354,784	51,422,066	63,880,076	52,068,506