Condensed Consolidated Statements of Cash Flows - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2022	Mar. 31, 2021
Cash flows from operating activities:
Net loss	$ (72,625)	$ (44,590)
Items not involving cash:
Depreciation of property and equipment	2,311	958
Amortization of intangible assets	155	1,090
Stock-based compensation recovery	(8,177)	(6,733)
Amortization of operating lease right-of-use assets	2,865	572
Deferred income tax expense	735	246
Change in fair value of contingent consideration liability	0	31
Change in fair value of investments in equity instruments	0	(167)
Unrealized foreign exchange loss	686	717
Changes in non-cash operating working capital:
Accounts receivable	11,325	10,717
Prepaid expenses and other current assets	(3,859)	(2,657)
Accounts payable and accrued liabilities	11,820	(163)
Operating lease liabilities	(648)	(824)
Net cash used in operating activities	(55,412)	(40,803)
Cash flows from financing activities:
Proceeds from public offering, net of issuance costs (note 8a)	107,720	0
Issuance of common shares on exercise of stock options (note 8e)	12	1,321
Issuance of common shares through employee stock purchase plan	863	829
Deferred financing fees	19	(40)
Finance lease payments	(4)	(4)
Net cash provided by financing activities	108,610	2,106
Cash flows from investing activities:
Net redemptions (purchases) of short-term investments	25,278	77,542
Acquisition of property and equipment	(4,158)	(695)
Acquisition of intangible assets	(546)	0
Net cash provided by investing activities	20,574	76,847
Effect of exchange rate changes on cash and cash equivalents	(123)	(239)
Net change in cash and cash equivalents	73,649	37,911
Cash and cash equivalents, beginning of period	201,867	242,036
Cash and cash equivalents, end of period	275,516	279,947
Supplemental disclosure of non-cash investing and financing items:
Leased assets obtained in exchange for operating lease liabilities	72	485
Acquisition of property and equipment in accounts payable and accrued liabilities	$ 1,590	$ 383