Shareholders' Equity - Schedule of Stock-based Compensation Expense for Equity Classified Instruments (Detail) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2022	Mar. 31, 2021
Research and Development Expense
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Stock-based compensation expense (recovery) for equity classified instruments	$ (2,747)	$ 4,336
Change in fair value of liability classified instruments	(474)	(2,513)
Total research and development, general and administration and finance expense (income)	(3,221)	1,823
General and Administrative Expenses
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Stock-based compensation expense (recovery) for equity classified instruments	(2,232)	4,192
Change in fair value of liability classified instruments	(2,876)	(12,951)
Total research and development, general and administration and finance expense (income)	(5,108)	(8,759)
Finance expense (income):
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Change in fair value of liability classified instruments	(30)	(66)
Total research and development, general and administration and finance expense (income)	$ (30)	$ (66)