Shareholders' Equity - Additional Information (Detail) - USD ($) $ / shares in Units, $ in Thousands						3 Months Ended		120 Months Ended
	Jan. 31, 2022	Jan. 27, 2020	Jun. 24, 2019	Jun. 07, 2018	Jul. 14, 2006	Mar. 31, 2022	Mar. 31, 2021	Dec. 31, 2028	Jan. 05, 2022	Dec. 31, 2021	Mar. 31, 2018
Subsidiary or Equity Method Investee [Line Items]
Preferred stock, shares issued						0				0
Preferred stock, shares outstanding (in shares)						0				0
Shares granted with respect to maximum fixed amount equal, percentage				20.00%	20.00%
Options granted under original plan exercisable period					10 years
Maximum number of common shares reserved for issuance (in shares)				5,686,097
Shares issuable upon exercise of stock options)											3,686,097
Number of shares available for grant						978,461				952,632
Proceeds from stock options exercised						$ 12
Expected average life of options						5 years 11 months 4 days	6 years 25 days
Unamortized compensation expense related to unvested options						$ 31,448
Remaining unamortized compensation expense, weighted-average period						1 year 9 months 3 days
Share-based compensation arrangement by share-based payment award, stock plan offering period						6 months
Total amount contributed by ESPP participants						$ 475				$ 1,243
Forecast
Subsidiary or Equity Method Investee [Line Items]
Maximum number of common shares reserved for issuance increase in percentage								4.00%
Inducement Plan
Subsidiary or Equity Method Investee [Line Items]
Number of common shares reserved for issuance									750,000
Restricted Share Units (RSUs)
Subsidiary or Equity Method Investee [Line Items]
Shares available for issuance under the Original Plan exercisable period						3 years
Award vesting rights, percentage						33.00%
Nonvested award, cost not yet recognized, amount						$ 2,678
Nonvested award, cost not yet recognized, period for recognition						1 year 4 months 2 days
Compensation charge						$ 604	$ 606
Employees Stock Purchase Plan
Subsidiary or Equity Method Investee [Line Items]
Compensation charge						$ 183	$ 269
Maximum eligible employees contribution under ESPP						15.00%
Purchase of shares under ESPP, maximum limit for each employee						$ 25
Offering
Subsidiary or Equity Method Investee [Line Items]
Number of shares issued (in shares)	11,035,000
Sale of stock (usd per share)	$ 8.00
Pre-funded warrants	3,340,000
Warrants issued price (in dollars per share)	$ 7.9999	$ 46.4999	$ 17.9999
Net proceeds from issuance	$ 107,534
Pre funded warrants issued in lieu of common shares to underwriters (in shares)		1,075,271	4,166,690
Exercise price of warrants (usd per share)	$ 0.0001	$ 0.0001	$ 0.0001
Over-Allotment Option
Subsidiary or Equity Method Investee [Line Items]
Number of shares issued (in shares)	1,875,000