Income Taxes - Summary of Significant Components of Deferred Income Tax Assets and Liabilities (Detail) - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
Deferred tax assets:
Non-capital losses carried forward	$ 123,554	$ 71,566
Deferred revenue	8,894	8,894
Share issue costs	6,058	8,365
Property and equipment	1,219	1,423
Intangible assets	2,911	1,352
Research and development deductions and credits	35,401	27,994
Contingent consideration	421	366
Stock options	4,330	2,038
Operating lease liability	7,871	1,837
Other	351	280
Gross deferred tax assets	191,010	124,115
Deferred tax liabilities:
Property and equipment	(1,085)	(1,296)
IPR&D	(4,760)	(4,760)
Operating lease right-of-use assets	(6,685)	(1,181)
Outside basis difference in foreign subsidiary	(1,573)	(1,178)
Gross deferred tax liabilities	(14,103)	(8,415)
Deferred tax assets liabilities before valuation allowance	176,907	115,700
Less: valuation allowance	(175,410)	(115,155)
Net deferred tax assets	1,497	545
Deferred tax asset	3,070	1,723
Deferred tax liability	(1,573)	(1,178)
Deferred Tax Net
Deferred tax liabilities:
Net deferred tax assets	$ 1,497	$ 545